Altshuler Ellery, Wheeler Sarah, Daily Karen
Department of Internal Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
Department of Hematology and Oncology, University of Florida College of Medicine, Gainesville, Florida, USA.
BMJ Case Rep. 2023 Jan 17;16(1):e251896. doi: 10.1136/bcr-2022-251896.
Pregnancy-associated cancer is defined as malignancy diagnosed during gestation or up to 1 year post partum. Treatment of cancer during pregnancy is complicated by the risk of harm to the fetus and limitations in safety data. Postpartum patients receiving chemotherapy, tyrosine-kinase inhibitors or hormonal agents should avoid breast feeding to avoid drug excretion in breast milk. Patients who will receive cytotoxic chemotherapy should be advised of the potential impact on their future fertility and offered fertility-preservation options. Breast cancer is the most common pregnancy-associated malignancy and is most frequently either invasive ductal or lobular carcinoma. Breast lymphoma is an exceedingly rare diagnosis that typically presents with unilateral disease in the seventh decade of life. Here, we present the case of a woman who presented with bilateral breast masses during the second trimester of pregnancy and was ultimately diagnosed with primary breast Burkitt's lymphoma.
妊娠相关癌症的定义为在妊娠期或产后1年内诊断出的恶性肿瘤。孕期癌症的治疗因对胎儿造成伤害的风险以及安全数据的局限性而变得复杂。接受化疗、酪氨酸激酶抑制剂或激素药物治疗的产后患者应避免母乳喂养,以避免药物通过母乳排泄。应告知将接受细胞毒性化疗的患者这对其未来生育能力的潜在影响,并为其提供生育力保存方案。乳腺癌是最常见的妊娠相关恶性肿瘤,最常见的是浸润性导管癌或小叶癌。乳腺淋巴瘤是一种极其罕见的诊断,通常在人生第七个十年出现单侧疾病。在此,我们报告一例在妊娠中期出现双侧乳腺肿块的女性病例,最终被诊断为原发性乳腺伯基特淋巴瘤。