Foreste Virginia, Della Corte Luigi, Stradella Cristina, Cusati Bianca, Coco Guido, Stradella Luigi
Department of Neuroscience, University of Naples Federico II, Naples, Italy, Reproductive Sciences and Dentistry, School of Medicine, Napoli, Italy.
Department of Department of Diagnostic Imaging, P.O. Santa Maria delle Grazie Asl Napoli 2 Nord., Napoli, Italy.
Eur J Breast Health. 2020 Dec 24;17(1):76-79. doi: 10.5152/ejbh.2020.5342. eCollection 2021 Jan.
Gigantomastia is a rare complication of pregnancy usually associated with benign conditions and rarely with malignancies. This paper reports a non-Hodgkin lymphoma case associated with gigantomastia during pregnancy. The patient was a 30-year-old gravida one woman, with a history of rapidly enlarging right breast at 2 weeks prior to presentation. After the first diagnosis of benign gigantomastia, the continuous growth of the breast, despite the delivery and bromocriptine therapy, required further investigation of the case. The histological analysis revealed the presence of Burkitt lymphoma. Malignant causes of unilateral gigantomastia in pregnancy should be considered in the differential diagnosis of this condition.
巨乳症是妊娠的一种罕见并发症，通常与良性疾病相关，很少与恶性肿瘤相关。本文报告了1例妊娠期间合并巨乳症的非霍奇金淋巴瘤病例。患者为一名30岁初孕妇，就诊前2周有右乳迅速增大病史。首次诊断为良性巨乳症后，尽管已分娩并接受溴隐亭治疗，但乳房仍持续增大，需要对该病例进行进一步检查。组织学分析显示为伯基特淋巴瘤。妊娠期间单侧巨乳症的恶性病因在该疾病的鉴别诊断中应予以考虑。
