Suppr超能文献

患有重症新型冠状病毒肺炎和暴发性社区获得性铜绿假单胞菌肺炎的年轻健康患者:病例报告

Young Healthy Patient With Severe COVID-19 and Fulminant Community-Acquired Pseudomonas aeruginosa Pneumonia: A Case Report.

作者信息

Kusaka Yusuke, Ogawa Taku, Yamada Tomoyuki, Minami Kenta, Umegaki Osamu, Ukimura Akira

机构信息

Department of Anesthesiology, Osaka Medical and Pharmaceutical University, Osaka, JPN.

Department of Microbilogy and Infection Control, Osaka Medical and Pharmaceutical University, Osaka, JPN.

出版信息

Cureus. 2022 Dec 16;14(12):e32617. doi: 10.7759/cureus.32617. eCollection 2022 Dec.

Abstract

Community-acquired pneumonia (CAP) caused by in healthy adults can rapidly lead to severe outcomes. We treated a case of -induced CAP and concurrent severe coronavirus disease (COVID-19) in a healthy 39-year-old man without other serious risk factors for severe illness except smoking. Immediately after admission, the patient developed sepsis and received intensive broad-spectrum antibacterial therapy with meropenem and vancomycin, veno-arterial extracorporeal membrane oxygenation (VAECMO), and catecholamine supplementation. Despite receiving multidisciplinary treatment, the patient died within 24 hours. with normal antimicrobial susceptibility was identified in blood and sputum cultures of samples taken at admission. Gram staining of the bacteria detected in blood cultures was suspicious for non-glucose-fermenting Gram-negative rods, including , and the antimicrobial regimen that was initiated following admission was considered effective. The patient was a plumber and a smoker, which are risk factors for induced CAP, and the clinical course matched those in previous reports of induced CAP, including necrotizing pneumonia with cavities and rapid progression of sepsis. Although COVID-19 can be the sole cause of septic shock, the combination of bacteremia and COVID-19 was possibly the cause of septic shock in this case. Even during an infectious disease pandemic, reviewing the patient's occupational history and comorbidities and performing blood and sputum culture tests, including Gram staining, are important for the provision of appropriate treatment.

摘要

健康成年人由[未提及具体病原体]引起的社区获得性肺炎(CAP)可迅速导致严重后果。我们治疗了一名39岁健康男性的[未提及具体病原体]所致CAP并并发严重冠状病毒病(COVID-19)的病例,该患者除吸烟外无其他严重疾病的危险因素。入院后,患者立即发生脓毒症,并接受了美罗培南和万古霉素的强化广谱抗菌治疗、静脉-动脉体外膜肺氧合(VA-ECMO)以及补充儿茶酚胺治疗。尽管接受了多学科治疗,患者仍在24小时内死亡。入院时采集的血液和痰液样本培养中分离出具有正常抗菌药敏性的[未提及具体病原体]。血培养中检测到的细菌革兰氏染色可疑为非葡萄糖发酵革兰氏阴性杆菌,包括[未提及具体病原体],入院后开始的抗菌治疗方案被认为是有效的。患者是一名水管工且吸烟,这些都是[未提及具体病原体]所致CAP的危险因素,其临床病程与既往[未提及具体病原体]所致CAP的报道相符,包括有空洞的坏死性肺炎和脓毒症的快速进展。虽然COVID-19可能是感染性休克的唯一原因,但[未提及具体病原体]菌血症和COVID-19的合并存在可能是该病例感染性休克的原因。即使在传染病大流行期间,回顾患者的职业史和合并症并进行血液和痰液培养检查,包括革兰氏染色,对于提供适当治疗也很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7f/9841129/a7d7a4801236/cureus-0014-00000032617-i01.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验