Hao Shaodong, Yang Shanshan, Zhang Naiwei, Cheng Hongjie
Spleen-Stomach Department, Fangshan Hospital, Beijing University of Chinese Medicine, Beijing, China.
Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Can J Infect Dis Med Microbiol. 2023 Jan 9;2023:6981721. doi: 10.1155/2023/6981721. eCollection 2023.
Fecal microbiota transplantation (FMT) is a current research hotspot, with a surge in the output of publications over the past decade. This study dedicates to the exploration of the research status and highlights significant themes and future trends in FMT research with the aid of bibliometric analysis.
FMT publications from 2012 to 2021 were retrieved on August 12, 2022, using the SCI-Expanded of Web of Science (WoS). The Bibliometrix in R program, Microsoft Office Excel, VOSviewer, and CiteSpace were utilized for bibliometrics and visual analysis, revealing the main publications, journals, countries, agencies, authors, and keywords distribution in FMT research.
There were 2,931 papers included. FMT research presented a growing trend from 2012 to 2021. The countries with the most publications and contributions in FMT area were China and the United States. The high-yield institutions were Harvard University, Udice French Research Universities, and the University of California System. The primary authors were Nieuwdorp Max, Allegretti Jessica R, and Kassam Zain. Frontiers in Microbiology and Science were the top-ranked journals in publications and total citations, respectively. The important topics primarily included FMT-related mechanisms and the usage of FMT in Clostridium difficile infection (CDI), inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), metabolic disease, neurological disorders, and psychiatric disorders. Future research would primarily concentrate on neurological disorders, chemotherapy and immunotherapy for malignant tumors, and FMT-related consensus and guidelines.
With the help of bibliometric analysis, we were able to obtain the understanding of the status and trends of global FMT-related research. The field of FMT is undergoing tremendous progress, and our findings can guide clinical researchers' and practitioners' future work in the rapidly evolving field of FMT.
粪便微生物群移植（FMT）是当前的研究热点，在过去十年中出版物产出激增。本研究致力于借助文献计量分析探索FMT研究的现状，并突出其重要主题和未来趋势。
于2022年8月12日使用科学网（WoS）的科学引文索引扩展版（SCI-Expanded）检索2012年至2021年的FMT出版物。利用R程序中的Bibliometrix、Microsoft Office Excel、VOSviewer和CiteSpace进行文献计量和可视化分析，揭示FMT研究中的主要出版物、期刊、国家、机构、作者和关键词分布。
共纳入2931篇论文。2012年至2021年FMT研究呈增长趋势。FMT领域出版物和贡献最多的国家是中国和美国。高产机构有哈佛大学、法国国家健康与医学研究院、加利福尼亚大学系统。主要作者有纽德波普·马克斯、阿莱格雷蒂·杰西卡·R和卡萨姆·扎因。《微生物学前沿》和《科学》分别是出版物数量和总被引次数排名靠前的期刊。重要主题主要包括FMT相关机制以及FMT在艰难梭菌感染（CDI）、炎症性肠病（IBD）、肠易激综合征（IBS）、代谢性疾病、神经障碍和精神障碍中的应用。未来研究将主要集中在神经障碍、恶性肿瘤的化疗和免疫治疗以及FMT相关的共识和指南。
借助文献计量分析，我们能够了解全球FMT相关研究的现状和趋势。FMT领域正在取得巨大进展，我们的研究结果可为临床研究人员和从业者在快速发展的FMT领域的未来工作提供指导。
