Bhandari Neelam R, Karegar Manjusha M, Vaideeswar Pradeep
Department of Pathology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
Indian J Pathol Microbiol. 2023 Jan-Mar;66(1):184-187. doi: 10.4103/ijpm.ijpm_379_21.
Phyllodes tumors (PTs) are uncommon biphasic breast neoplasms constituting 0.5 to 1.0% of all breast tumors. Malignant PTs form a very small proportion of these and may metastasize, especially to the lungs and bones. Aggression and metastatic potential are accentuated in tumors exhibiting heterologous differentiation. Metastases to the gastrointestinal tract (GIT) have seldom been reported and are often confined to a segment of the digestive tract. In the absence of relevant clinical history, such patients presenting with gastrointestinal symptoms can lead to diagnostic perplexities. We report a unique case of a malignant PT with extensive osteosarcomatous differentiation and widespread metastases to the GIT.
叶状肿瘤（PTs）是一种罕见的双相性乳腺肿瘤，占所有乳腺肿瘤的0.5%至1.0%。恶性PTs在其中所占比例极小，且可能发生转移，尤其是转移至肺和骨。在表现出异源性分化的肿瘤中，侵袭性和转移潜能会增强。胃肠道转移很少见，且通常局限于消化道的某一段。在缺乏相关临床病史的情况下，出现胃肠道症状的此类患者可能会导致诊断困惑。我们报告了一例独特的病例，该恶性PT具有广泛的骨肉瘤样分化，并广泛转移至胃肠道。
