Department of Psychiatry and Behavioral Sciences.
Psychol Trauma. 2023 Jan;15(1):100-109. doi: 10.1037/tra0001257. Epub 2022 May 12.
Although there is mounting evidence that massed treatment for PTSD is both feasible and effective, many questions remain about the optimal length of intensive treatment programs (ITPs), as well as the role of adjunctive services, such as psychoeducation, mindfulness, and yoga. Our setting recently transitioned from a three-week ITP to a two-week program. Adjunctive services were reduced, but the amount of individual CPT between programs remained similar. The present study examined the effectiveness of a two-week ITP based on twice daily individual CPT sessions and evaluated the program's noninferiority to an established three-week ITP using a Bayesian analytical approach.
Bayesian linear mixed regression models were used to explore PTSD and depression changes over time, as well as predictors of change. Noninferiority of the two-week ITP to a three-week ITP was also established using a Bayes factor approach.
Results indicate that program participants change meaningfully in both PTSD and depression severity over the course of treatment, and that changes in posttraumatic cognitions predict subsequent changes in these outcomes. Further, the two-week ITP can be considered noninferior to the three-week ITP in both clinical outcomes and overall satisfaction.
In the context of intensive PTSD treatment, the content of the ITP appears to matter more than its overall length. Shorter programs have the potential to increase access and treatment capacity. Our findings demonstrate the importance of continuous and rigorous program evaluation. Limitations as well as future directions for research, such as identifying the most effective treatment components, are discussed. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
尽管越来越多的证据表明集中治疗创伤后应激障碍(PTSD)既可行又有效,但关于强化治疗方案(ITP)的最佳长度以及心理教育、正念和瑜伽等辅助服务的作用仍存在许多问题。我们的环境最近从为期三周的 ITP 过渡到为期两周的方案。辅助服务减少了,但两次方案之间的个体认知加工疗法(CPT)数量仍相似。本研究根据每日两次的个体 CPT 来检验为期两周的 ITP 的有效性,并使用贝叶斯分析方法评估该方案相对于既定的为期三周的 ITP 的非劣效性。
使用贝叶斯线性混合回归模型来探讨 PTSD 和抑郁症状随时间的变化以及变化的预测因素。还使用贝叶斯因子方法来确定为期两周的 ITP 相对于为期三周的 ITP 的非劣效性。
结果表明,在治疗过程中,方案参与者在 PTSD 和抑郁严重程度方面都有明显的变化,并且创伤后认知的变化预测了这些结果的后续变化。此外,在临床结果和总体满意度方面,为期两周的 ITP 可以被认为与为期三周的 ITP 相当。
在密集 PTSD 治疗的背景下,ITP 的内容似乎比其整体长度更重要。较短的方案有可能增加可及性和治疗能力。我们的研究结果强调了持续和严格的方案评估的重要性。讨论了限制以及未来的研究方向,例如确定最有效的治疗成分。(PsycInfo 数据库记录(c)2023 APA,保留所有权利)。