Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.
Department of Psychiatry, University of Illinois - Chicago, Chicago, IL, USA.
Eur J Psychotraumatol. 2024;15(1):2350908. doi: 10.1080/20008066.2024.2350908. Epub 2024 May 21.
Growing evidence indicates that daily delivery of evidence-based PTSD treatments (e.g. Cognitive Processing Therapy (CPT)), as part of intensive PTSD treatment programmes (ITPs), is feasible and effective. Research has demonstrated that a 2-week CPT-based ITP can produce equivalent outcomes to a 3-week ITP, suggesting shorter treatment can also be highly effective. However, the extent to which ITP length and composition impact longer-term outcomes needs further study. We examined whether PTSD and depression symptoms 3-, 6-, and 12-months following completion of a 2-week ITP could be considered non-inferior, or equivalent, to those of a 3-week ITP. Data from 638 veterans who participated in a 2-week CPT-based ITP were evaluated against 496 veterans who participated in a 3-week CPT-based ITP. A Bayes factor approach was used to examine whether PTSD and depression severity outcomes of the 2-week ITP could be considered equivalent to the 3-week ITP. Participants across both ITPs reported large PTSD ( = 0.98) and moderate to large depression symptom reductions ( = 0.69) from baseline to 12-month follow-up. The PTSD and depression symptom reductions seen in the 2-week ITP were determined to be equivalent to those of the 3-week ITP. Low follow-up completion was a limitation. Future research might replicate the present findings using samples with greater follow-up rates and explore whether adjunctive services impact other relevant constructs, such as quality of life and functioning.
越来越多的证据表明，将基于证据的 PTSD 治疗（例如认知加工疗法（CPT））作为强化 PTSD 治疗计划（ITP）的一部分，每天提供是可行且有效的。研究表明，为期 2 周的基于 CPT 的 ITP 可以产生与为期 3 周的 ITP 相当的结果，这表明较短的治疗也可以非常有效。然而，ITP 的长度和组成对长期结果的影响程度需要进一步研究。我们研究了在完成为期 2 周的 ITP 后 3、6 和 12 个月时 PTSD 和抑郁症状是否可以被认为与 3 周的 ITP 无差异或等效。对参加为期 2 周的基于 CPT 的 ITP 的 638 名退伍军人的数据进行了评估，同时对参加为期 3 周的基于 CPT 的 ITP 的 496 名退伍军人的数据进行了评估。采用贝叶斯因子方法来检查 2 周 ITP 的 PTSD 和抑郁严重程度结果是否可以被认为与 3 周 ITP 等效。两个 ITP 中的参与者都报告说，从基线到 12 个月的随访，PTSD（ = 0.98）和中度至重度抑郁症状都有较大幅度的减轻（ = 0.69）。2 周 ITP 中观察到的 PTSD 和抑郁症状减轻被认为与 3 周 ITP 等效。随访完成率低是一个限制。未来的研究可能会使用随访率更高的样本复制本研究的发现，并探讨辅助服务是否会影响其他相关结构，如生活质量和功能。
