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基于聚合物的柔性生物电子学。

Polymer-based flexible bioelectronics.

作者信息

Wu Xiaoying, Peng Huisheng

机构信息

State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, and Laboratory of Advanced Materials, Fudan University, Shanghai 200438, China.

State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, and Laboratory of Advanced Materials, Fudan University, Shanghai 200438, China.

出版信息

Sci Bull (Beijing). 2019 May 15;64(9):634-640. doi: 10.1016/j.scib.2019.04.011. Epub 2019 Apr 5.

Abstract

Due to the mechanical mismatch between conventional rigid electronic devices and soft tissues at nature, a lot of interests have been attracted to develop flexible bioelectronics that work well both in vitro and in vivo. To this end, polymers that can be used for both key components and substrates are indispensable to achieve high performances such as high sensitivity and long-term stability for sensing applications. Here we will summarize the recent advances on the synthesis of a variety of polymers, the design of typical architectures and the integration of different functions for the flexible bioelectronic devices. The remaining challenges and promising directions are highlighted to provide inspirations for the future study on the emerging flexible bioelectronics at end.

摘要

由于传统刚性电子设备与天然软组织之间存在机械不匹配,开发在体外和体内均能良好工作的柔性生物电子学引起了广泛关注。为此,可用于关键组件和基板的聚合物对于实现诸如传感应用中的高灵敏度和长期稳定性等高性能而言不可或缺。在此,我们将总结在柔性生物电子器件的各种聚合物合成、典型结构设计以及不同功能集成方面的最新进展。最后强调了剩余的挑战和有前景的方向,为新兴柔性生物电子学的未来研究提供启示。

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