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[痛风更新]

[Update Gout].

作者信息

Ankli Barbara, Daikeler Thomas

机构信息

Departement Rheumatologie, Schmerzklinik Basel, Schweiz.

Medizinische Fakultät, Universität Basel, Schweiz.

出版信息

Ther Umsch. 2023 Feb;80(1):17-26. doi: 10.1024/0040-5930/a001402.

Abstract

Update Gout Gout, the most frequent arthritis worldwide, is seldomly considered a serious chronic disease. Cardiovascular morbidity and allover mortality are increased in gout patients. Prevalence of gout is very variable in different countries and is estimated to be 2.6% overall. Men are overrepresented (3:1 to 4:1). Environmental factors, such as diet and alcohol intake, are still important, but the genetic influence, e.g., in early-onset gout, gets more and more attention. Despite the broad range of therapeutic options outcomes are poor, and the disease often leads to disabling structural damages, not only in joints. Patients' education, and the involvement of trained general practitioners and nurses will hopefully improve the outcomes of this treatable disease.

摘要

痛风的最新情况 痛风是全球最常见的关节炎,很少被视为一种严重的慢性疾病。痛风患者的心血管发病率和全因死亡率均有所增加。痛风在不同国家的患病率差异很大,总体估计为2.6%。男性患者居多(比例为3:1至4:1)。饮食和酒精摄入等环境因素仍然很重要,但遗传因素,例如早发性痛风,受到越来越多的关注。尽管有广泛的治疗选择,但治疗效果不佳,而且该疾病不仅会导致关节出现致残性结构损伤。患者教育以及训练有素的全科医生和护士的参与有望改善这种可治疗疾病的治疗效果。

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