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定制软性圆锥角膜镜片对圆锥角膜患者角膜像差和光学现象的疗效:一项基于角膜地形图成像的研究。

Efficacy of custom-made soft keratoconus lenses on corneal aberrations and photic phenomena in patients with keratoconus: a corneal topography imaging based study.

作者信息

Penbe Aysegul, Kanar Hatice Selen, Arsan Aysu Karatay, Kurna Sevda Aydın

机构信息

Department of Ophthalmology, Kartal Dr. Lutfi Kirdar Training and Research Hospital, Health Science University, Semsi Denizer Caddesi, E-5, Kartal Istanbul 34890, Turkey.

Department of Ophthalmology, Fatih Sultan Mehmet Training and Research Hospital, Health Science University, E-5, Icerenkoy 34752, Istanbul, Turkey.

出版信息

Int J Ophthalmol. 2023 Jan 18;16(1):67-74. doi: 10.18240/ijo.2023.01.10. eCollection 2023.

DOI:10.18240/ijo.2023.01.10
PMID:36659953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9815985/
Abstract

AIM

To evaluate the efficacy of custom-made soft keratoconus (KC) lenses on corneal aberrations and photic phenomena in two different optical zones in patients with KC.

METHODS

Sixty eyes of 42 patients with KC were examined at baseline and after fitting HydroCone (Toris K) soft silicone hydrogel lenses. Best spectacle-corrected visual acuity (BSCVA) and contact lens-corrected visual acuity (CLCVA) were recorded. Lower- and higher-order corneal aberrations (LOAs and HOAs) were measured with and without Toris K lenses and compared in central 4.5 mm and 7 mm zones. Mesopic pupil diameter and subjective photic phenomena were also assessed.

RESULTS

Mean CLCVA was significantly improved compared to BSCVA (<0.0001). Corneal curvature and refractive measurements were found to be significantly reduced by the use of Toris K lenses, except for posterior corneal curvature values. In the 4.5 mm central optical zone, all wavefront aberrations decreased significantly after lens fitting (<0.0001). In contrast, in the 7 mm (peripheral) optical zone, values for HOAs, spherical and residual aberrations, and optical path differences were increased, while LOAs, trefoil, and quadrifoil coefficients were decreased. The rate of photic phenomena was significantly higher in participants with a pupil size >6.00 mm (85.7%).

CONCLUSION

Toris K lenses provide good visual results and a significant reduction in central corneal aberrations in patients with KC but could cause an increase in peripheral aberrations. This practical and nonsurgical approach appears to be an effective method for the visual management of KC.

摘要

目的

评估定制的软性圆锥角膜(KC)镜片对KC患者两个不同光学区角膜像差和光学现象的疗效。

方法

对42例KC患者的60只眼在基线时以及佩戴HydroCone(Toris K)软性硅水凝胶镜片后进行检查。记录最佳眼镜矫正视力(BSCVA)和隐形眼镜矫正视力(CLCVA)。在佩戴和不佩戴Toris K镜片的情况下测量角膜低阶和高阶像差(LOAs和HOAs),并在中央4.5毫米和7毫米区域进行比较。还评估了中瞳孔直径和主观光学现象。

结果

与BSCVA相比,平均CLCVA有显著改善(<0.0001)。发现使用Toris K镜片后角膜曲率和屈光测量值显著降低,但角膜后表面曲率值除外。在4.5毫米中央光学区,镜片佩戴后所有波前像差均显著降低(<0.0001)。相比之下,在7毫米(周边)光学区,HOAs、球差和残余像差以及光程差的值增加,而LOAs、三叶像差和四叶像差系数降低。瞳孔大小>6.00毫米的参与者中光学现象的发生率显著更高(85.7%)。

结论

Toris K镜片为KC患者提供了良好的视觉效果,并显著降低了中央角膜像差,但可能导致周边像差增加。这种实用的非手术方法似乎是KC视觉管理的有效方法。

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本文引用的文献

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Diagnosis of Subclinical Keratoconus Based on Machine Learning Techniques.基于机器学习技术的亚临床圆锥角膜诊断
J Clin Med. 2021 Sep 21;10(18):4281. doi: 10.3390/jcm10184281.
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Treatment of Keratoconus with WaveLight Contoura and Corneal Cross-Linking Combined.采用威视康耐视和角膜交联联合治疗圆锥角膜
Clin Ophthalmol. 2021 Jun 14;15:2455-2472. doi: 10.2147/OPTH.S303559. eCollection 2021.
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Contrast sensitivity and higher-order aberrations in Keratoconus subjects.圆锥角膜患者的对比敏感度和高阶像差。
Sci Rep. 2021 Jun 21;11(1):12971. doi: 10.1038/s41598-021-92396-5.
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Optimizing correction of coma aberration in keratoconus with a novel soft contact lens.用新型软接触镜优化圆锥角膜的彗差矫正。
Cont Lens Anterior Eye. 2021 Aug;44(4):101405. doi: 10.1016/j.clae.2020.12.071. Epub 2021 Jan 10.
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Optical Quality in Keratoconus Is Associated With Corneal Biomechanics.圆锥角膜的光学质量与角膜生物力学有关。
Cornea. 2021 Oct 1;40(10):1276-1281. doi: 10.1097/ICO.0000000000002631.
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Clinical utility of irx3 in keratoconus.IRX3 在圆锥角膜中的临床应用。
Clin Exp Optom. 2021 Jan;104(1):107-114. doi: 10.1111/cxo.13133.
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Update on Contact Lens Treatment of Keratoconus.圆锥角膜角膜接触镜治疗的最新进展。
Turk J Ophthalmol. 2020 Aug 26;50(4):234-244. doi: 10.4274/tjo.galenos.2020.70481.
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Eye (Lond). 2020 Dec;34(12):2175-2196. doi: 10.1038/s41433-020-1065-z. Epub 2020 Jul 8.
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Do visual performance and optical quality vary across different contact lens correction modalities in keratoconus?圆锥角膜患者中,不同的隐形眼镜矫正方式在视觉表现和光学质量上是否存在差异?
Cont Lens Anterior Eye. 2020 Dec;43(6):568-576. doi: 10.1016/j.clae.2020.03.009. Epub 2020 Mar 29.