甲型肝炎病毒感染与噬血细胞综合征相关
HAV Infection Associated with Hemophagocytic Syndrome.
作者信息
Aamri H, Elqadiry R, Nassih H, Bourrahouat A, Ait Sab I
机构信息
Department of Pediatrics, Children's University Hospital, Marrakech, Morocco.
Child Health and Development Research Unit, Cadi Ayyad University, Marrakech, Morocco.
出版信息
Case Rep Infect Dis. 2023 Jan 10;2023:7799252. doi: 10.1155/2023/7799252. eCollection 2023.
Hemophagocytic syndrome is a rare disease that can cause severe illness and death. This condition is caused by the presence of antibodies against the hepatitis A virus. A positive anti-IGM antibody was identified in our 7-year-old patient with severe hepatitis A. A week after the hepatitis A was diagnosed, the patient experienced pancytopenia, which was worsened by prolonged fever. He was then diagnosed with macrophage activation syndrome. The treatment with steroids improved the clinical and biological evolution of the condition.
噬血细胞综合征是一种可导致严重疾病和死亡的罕见疾病。这种情况是由抗甲型肝炎病毒抗体的存在引起的。在我们一名患有严重甲型肝炎的7岁患者中检测到抗IgM抗体呈阳性。甲型肝炎确诊一周后，患者出现全血细胞减少，长期发热使其病情恶化。随后他被诊断为巨噬细胞活化综合征。使用类固醇治疗改善了病情的临床和生物学进展。
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