鸡降钙素基因的序列与表达
Sequence and expression of the chicken calcitonin gene.
作者信息
Minvielle S, Cressent M, Delehaye M C, Segond N, Milhaud G, Jullienne A, Moukhtar M S, Lasmoles F
机构信息
U 113 INSERM, CHU St. Antoine, Paris, France.
出版信息
FEBS Lett. 1987 Oct 19;223(1):63-8. doi: 10.1016/0014-5793(87)80510-0.
PMID:3666142
Abstract
The avian calcitonin gene was isolated and sequenced; two mRNAs are expressed by tissue-specific alternate splicing. The peptides encoded by the mRNAs are the protein precursors of either calcitonin or calcitonin gene-related peptide (CGRP). Calcitonin is expressed predominantly in ultimobranchial bodies and CGRP in brain.
摘要
鸟类降钙素基因被分离并测序；两种mRNA通过组织特异性可变剪接表达。这些mRNA编码的肽是降钙素或降钙素基因相关肽（CGRP）的蛋白质前体。降钙素主要在鳃后体中表达，而CGRP在脑中表达。
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