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基于研究主题和趋势的废水流行病学发展知识图谱:数据驱动分析。

Knowledge graph of wastewater-based epidemiology development: A data-driven analysis based on research topics and trends.

机构信息

School of Environment and Energy, South China University of Technology, Higher Education Mega Center, 510006, Guangzhou, China.

School of Computer Science and Engineering, South China University of Technology, 510006, Guangzhou, China.

出版信息

Environ Sci Pollut Res Int. 2023 Mar;30(11):28373-28382. doi: 10.1007/s11356-023-25237-9. Epub 2023 Jan 20.

DOI:10.1007/s11356-023-25237-9
PMID:36662433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9867605/
Abstract

Wastewater-based epidemiology (WBE) has contributed significantly to the monitoring of drug use and transmission of viruses that has been published in numerous research papers. In this paper, we used LitStraw, a self-developed text extraction tool, to extract, analyze, and construct knowledge graphs from nearly 900 related papers in PDF format collected in Web of Science from 2000 to 2021 to analyze the research hotspots and development trends of WBE. The results showed a growing number of WBE publications in multidisciplinary cross-collaboration, with more publications and close collaboration between the USA, Australia, China, and European countries. The keywords of illicit drugs and pharmaceuticals still maintain research hotness, but the specific research hotspots change significantly, among which the research hotspots of new psychoactive substances, biomarkers, and stability show an increasing trend. In addition, judging the spread of COVID-19 by the presence of SARS-CoV-2 RNA in sewage has become the focus since 2020. This work can show the development of WBE more clearly by constructing a knowledge graph and also provide new ideas for the paper mining analysis methods in different fields.

摘要

基于污水的流行病学(WBE)在监测药物使用和病毒传播方面做出了重大贡献,相关研究已发表在大量研究论文中。在本文中,我们使用自主研发的文本提取工具 LitStraw,从 2000 年至 2021 年在 Web of Science 上收集的近 900 篇 PDF 格式的相关论文中提取、分析和构建知识图谱,以分析 WBE 的研究热点和发展趋势。结果表明,多学科交叉合作的 WBE 出版物不断增加,美国、澳大利亚、中国和欧洲国家的出版物和合作更加密切。非法药物和药物的关键词仍然保持着研究热度,但具体的研究热点变化显著,其中新精神活性物质、生物标志物和稳定性的研究热点呈上升趋势。此外,自 2020 年以来,通过污水中 SARS-CoV-2 RNA 的存在来判断 COVID-19 的传播已成为研究重点。通过构建知识图谱,可以更清楚地展示 WBE 的发展情况,也为不同领域的论文挖掘分析方法提供了新的思路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de9/9867605/eeb51d6eb8c7/11356_2023_25237_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de9/9867605/473807eba637/11356_2023_25237_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de9/9867605/7f125179bb69/11356_2023_25237_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de9/9867605/eeb51d6eb8c7/11356_2023_25237_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de9/9867605/473807eba637/11356_2023_25237_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de9/9867605/7f125179bb69/11356_2023_25237_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de9/9867605/eeb51d6eb8c7/11356_2023_25237_Fig3_HTML.jpg

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Automatic analytical approach for the determination of 12 illicit drugs and nicotine metabolites in wastewater using on-line SPE-UHPLC-MS/MS.
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