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患有泰里恩边缘性角膜变性患者泪液中的溶酶体酶

Lysosomal enzymes in tear fluids from patients with Terrien's marginal corneal degeneration.

作者信息

Hayasaka S, Tsuchiya M, Sekimoto M, Noda S, Shibuya Y, Setogawa T

机构信息

Department of Ophthalmology, Shimane Medical University, Japan.

出版信息

Graefes Arch Clin Exp Ophthalmol. 1987;225(5):335-7. doi: 10.1007/BF02153400.

DOI:10.1007/BF02153400
PMID:3666476
Abstract

We examined biochemically the lysosomal enzyme activities in tear fluids from patients with mild myopia, senile cataract, and Terrien's marginal corneal degeneration. Tear acid phosphatase activities in Terrien's degeneration were almost the same as those in mild myopia and senile cataract, while those of N-acetyl-beta-D-glucosaminidase in Terrien's degeneration were higher. The high activity of tear N-acetyl-beta-D-glucosaminidase may be derived from the lacrimal gland and infiltrate histiocytelike cells in Terrien's marginal corneal degeneration.

摘要

我们对轻度近视、老年性白内障和泰里恩边缘性角膜变性患者泪液中的溶酶体酶活性进行了生化检测。泰里恩变性患者泪液中的酸性磷酸酶活性与轻度近视和老年性白内障患者的几乎相同,而泰里恩变性患者的N-乙酰-β-D-氨基葡萄糖苷酶活性较高。泪液中N-乙酰-β-D-氨基葡萄糖苷酶的高活性可能来源于泪腺,并浸润泰里恩边缘性角膜变性中的组织细胞样细胞。

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1
Lysosomal enzymes in tear fluids from patients with Terrien's marginal corneal degeneration.患有泰里恩边缘性角膜变性患者泪液中的溶酶体酶
Graefes Arch Clin Exp Ophthalmol. 1987;225(5):335-7. doi: 10.1007/BF02153400.
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Immunohistochemistry of Terrien's and Mooren's corneal degeneration.泰里恩角膜变性和莫伦角膜变性的免疫组织化学
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本文引用的文献

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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Inflammatory Terrien's marginal corneal disease.炎症性泰里恩边缘性角膜病
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Terrien's marginal corneal degeneration.泰里恩边缘性角膜变性
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Pathology of Terrien's disease. Histochemical and electron microscopic study.特里安病的病理学。组织化学和电子显微镜研究。
Am J Ophthalmol. 1972 Dec;74(6):1191-200. doi: 10.1016/0002-9394(72)90742-8.
5
Lysosomal enzymes in human tear fluid collected by filter paper strips.
Exp Eye Res. 1985 Sep;41(3):259-65. doi: 10.1016/s0014-4835(85)80015-4.
6
Lysosomal enzymes in tear fluids from patients with ocular diseases.眼部疾病患者泪液中的溶酶体酶。
Jpn J Ophthalmol. 1986;30(2):154-7.