Kitaoka M, Yamaguchi K, Hayasaka S
Jpn J Ophthalmol. 1986;30(2):154-7.
Lysosomal enzyme activities in the tear fluids were determined in patients with ocular diseases. Acid phosphatase, beta-D-glucuronidase, N-acetyl-beta-D-glucosaminidase, and beta-D-mannosidase activities were almost the same among the tear fluids from patients with myopia, rhegmatogenous retinal detachment, simple diabetic retinopathy and pigmentary retinal dystrophy. In contrast, the activities were lower in the affected eyes of patients with herpetic keratitis and vernal conjunctivitis than in the fellow normal eyes. It is possible that the lysosomal enzyme activities in the tears may be closely related to the condition of the external eye disease.
对患有眼部疾病的患者的泪液中的溶酶体酶活性进行了测定。在近视、孔源性视网膜脱离、单纯糖尿病性视网膜病变和色素性视网膜营养不良患者的泪液中，酸性磷酸酶、β-D-葡萄糖醛酸酶、N-乙酰-β-D-氨基葡萄糖苷酶和β-D-甘露糖苷酶的活性几乎相同。相比之下，疱疹性角膜炎和春季结膜炎患者患眼的这些酶活性低于对侧正常眼。泪液中的溶酶体酶活性可能与外眼疾病的状况密切相关。
