Manriquez Diego, Costa Maiara, Ferchiou Ahmed, Raboisson Didier, Lhermie Guillaume
CIRAD, ASTRE, Université de Toulouse, ENVT, 31300 Toulouse, France.
Department of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Antibiotics (Basel). 2022 Dec 21;12(1):8. doi: 10.3390/antibiotics12010008.
To respond to the antimicrobial resistance (AMR) threat, public health entities implement policies aiming to reduce antimicrobial use (AMU) in livestock systems, in which policy success and sustainability might be subject to the social acceptability of the novel regulatory environment. Therefore, consistent methods that gather and synthesize preferences of stakeholder groups are needed during the policy design. The objective of this study was to present a methodology for evaluating the acceptability of potential strategies to reduce AMU using multi-criteria decision analysis (MCDA) using French dairy industry as a model. Preference-ranking organization methods for enrichment evaluations were applied to rank stakeholders' acceptance of four different potential AMU reduction strategies: 1. Baseline AMU regulations in France; 2. Total interdiction of AMU; 3. Interdiction of prophylaxis and metaphylaxis AMU; and 4. Subsidies to reduce AMU by 25%. A total of 15 stakeholders (consumers, = 10; farmers, = 2; public health representatives, = 3) representing the French dairy sector and public health administration participated in the acceptance weighting of the strategies in relation with their impact on environmental, economic, social, and political criteria. We established a MCDA methodology and result-interpretation approach that can assist in prioritizing alternatives to cope with AMR in the French dairy industry or in other livestock systems. Our MCDA framework showed that consumers and public health representatives preferred alternatives that consider the restriction of AMU, whereas farmers preferred to maintain baseline policy.
为应对抗菌药物耐药性（AMR）威胁，公共卫生实体实施旨在减少畜牧系统中抗菌药物使用（AMU）的政策，而政策的成功与可持续性可能取决于新监管环境的社会可接受性。因此，在政策设计过程中需要有一致的方法来收集和综合利益相关者群体的偏好。本研究的目的是以法国乳制品行业为模型，提出一种使用多标准决策分析（MCDA）评估减少AMU潜在策略可接受性的方法。应用用于丰富评估的偏好排序组织方法，对利益相关者对四种不同的潜在AMU减少策略的接受程度进行排序：1. 法国的基线AMU法规；2. 完全禁止AMU；3. 禁止预防性和群体预防性AMU；4. 补贴以将AMU减少25%。共有15名代表法国乳制品行业和公共卫生管理部门的利益相关者（消费者，n = 10；农民，n = 2；公共卫生代表，n = 3）参与了对这些策略在环境、经济、社会和政治标准方面影响的接受程度加权。我们建立了一种MCDA方法和结果解释方法，可协助对法国乳制品行业或其他畜牧系统中应对AMR的替代方案进行优先排序。我们的MCDA框架表明，消费者和公共卫生代表更喜欢考虑限制AMU的替代方案，而农民则更喜欢维持基线政策。
