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肾移植后的长期眼科随访

[Long-term ophthalmologic follow-up after kidney transplantation].

作者信息

Kopsa H, Bettelheim H, Grabner G, Schmidt P, Zazgornik J, Balcke P, Pils P

出版信息

Schweiz Med Wochenschr. 1978 Dec 30;108(52):2069-72.

PMID:366745
Abstract

16 renal transplant recipients underwent ophthalmological examination 11.4, 19.4 and 61.3 months after renal transplantation. The most common side effects of immunosuppressive therapy were steroid-induced cataract formation, steroid glaucoma, and recurrent subconjunctival haemorrhages. Posterior sub-capsular cataracts may develop as early as 2 months after surgery, reach their highest incidence within 2 years and may be reversible under low dosage steroid therapy. 75.5% of 57 ophthalmologically examined patients showed ocular complications or changes, but visual function was not severely disturbed. Despite hypertension in 23 cases, no hypertensive retinopathy was observed. In the light of these findings we assume that kidney transplantation has a positive influence on ocular functions, and especially on fundus changes dating from the time of regular dialysis treatment.

摘要

16名肾移植受者在肾移植后11.4个月、19.4个月和61.3个月接受了眼科检查。免疫抑制治疗最常见的副作用是类固醇诱导的白内障形成、类固醇性青光眼和复发性结膜下出血。后囊下白内障可能在手术后2个月就开始出现,在2年内发病率最高,并且在低剂量类固醇治疗下可能是可逆的。57名接受眼科检查的患者中有75.5%出现眼部并发症或变化,但视觉功能未受到严重干扰。尽管有23例患者患有高血压,但未观察到高血压性视网膜病变。根据这些发现,我们认为肾移植对眼部功能有积极影响,尤其是对定期透析治疗时期就已存在的眼底病变有积极影响。

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