Shimmyo A, Miyazaki S, Onoe S, Nojima M, Ihara H, Ikoma F
Department of Ophthalmology, Hyogo College of Medicine, Japan.
Nippon Ganka Gakkai Zasshi. 1997 Mar;101(3):220-6.
Seventy-two post-renal transplant patients were studied for ocular complications. Of 72 patients, 56 (77.8%) showed some ocular abnormality. Steroid cataract was the most common complication, occurring in 45 patients (62.5%). Eleven patients (18 eyes) had undergone operations for cataract. The average of their ages was 39.7 years and the period from renal transplantation to cataract operation was 3.3 years. Postoperative visual acuity was over 20/20 in most cases. Increased intraocular pressure was encountered in 9 patients (12.5%), cytomegalovirus ocular infection in 2 (2.8%), hypertensive retinopathy in 2 (2.8%), branch retinal vein occlusion in 1 (1.4%), and subconjunctival hemorrhage in 15 (20.8%). A new immunosuppressant, cyclosporine, increased renal graft survival more than azathioprine. However, ocular complications such as steroid cataract occurred frequently in spite of the use of cyclosporine, as in the azathioprine era. In conclusion, it is necessary for renal transplant patients to receive a periodical ophthalmological check-up.
对72例肾移植术后患者的眼部并发症进行了研究。在这72例患者中，56例（77.8%）出现了一些眼部异常。类固醇性白内障是最常见的并发症，45例患者（62.5%）出现该并发症。11例患者（18只眼）接受了白内障手术。他们的平均年龄为39.7岁，从肾移植到白内障手术的时间为3.3年。大多数病例术后视力超过20/20。9例患者（12.5%）出现眼压升高，2例（2.8%）出现巨细胞病毒性眼部感染，2例（2.8%）出现高血压性视网膜病变，1例（1.4%）出现视网膜分支静脉阻塞，15例（20.8%）出现结膜下出血。一种新的免疫抑制剂环孢素比硫唑嘌呤更能提高肾移植的存活率。然而，尽管使用了环孢素，但类固醇性白内障等眼部并发症仍频繁发生，与硫唑嘌呤时代一样。总之，肾移植患者定期进行眼科检查是必要的。
