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High triglycerides and low high-density lipoprotein cholesterol lipid profile in rheumatoid arthritis: A potential link among inflammation, oxidative status, and dysfunctional high-density lipoprotein.类风湿关节炎患者的甘油三酯升高和高密度脂蛋白胆固醇降低的脂质谱:炎症、氧化状态和功能失调的高密度脂蛋白之间的潜在联系。
J Clin Lipidol. 2017 Jul-Aug;11(4):1043-1054.e2. doi: 10.1016/j.jacl.2017.05.009. Epub 2017 Jun 3.
2
Prevalence of rheumatoid arthritis in low- and middle-income countries: A systematic review and analysis.低收入和中等收入国家类风湿关节炎的患病率:一项系统评价与分析
J Glob Health. 2015 Jun;5(1):010409. doi: 10.7189/jogh.05.010409.
3
Asymptomatic atherosclerosis in egyptian rheumatoid arthritis patients and its relation to disease activity.埃及类风湿关节炎患者的无症状动脉粥样硬化及其与疾病活动的关系。
Int J Rheumatol. 2015;2015:381931. doi: 10.1155/2015/381931. Epub 2015 Feb 8.
4
Interaction of differentiated human adipocytes with macrophages leads to trogocytosis and selective IL-6 secretion.分化的人脂肪细胞与巨噬细胞的相互作用导致胞饮作用和选择性的 IL-6 分泌。
Cell Death Dis. 2015 Jan 22;6(1):e1613. doi: 10.1038/cddis.2014.579.
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The effect of sauna bathing on lipid profile in young, physically active, male subjects.桑拿浴对年轻、身体活跃的男性受试者血脂水平的影响。
Int J Occup Med Environ Health. 2014 Aug;27(4):608-18. doi: 10.2478/s13382-014-0281-9. Epub 2014 Jul 7.
6
Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment.类风湿关节炎中的心血管风险:对炎症的关键作用、风险预测因素及治疗影响的最新认识进展
Rheumatology (Oxford). 2014 Dec;53(12):2143-54. doi: 10.1093/rheumatology/keu224. Epub 2014 Jun 6.
7
Rheumatoid arthritis and cardiovascular disease.类风湿关节炎与心血管疾病。
Am Heart J. 2013 Oct;166(4):622-628.e1. doi: 10.1016/j.ahj.2013.07.010. Epub 2013 Aug 29.
8
Neuropeptides activate TRPV1 in rheumatoid arthritis fibroblast-like synoviocytes and foster IL-6 and IL-8 production.神经肽激活类风湿性关节炎成纤维细胞样滑膜细胞中的TRPV1,并促进白细胞介素-6和白细胞介素-8的产生。
Ann Rheum Dis. 2013 Jun;72(6):1107-9. doi: 10.1136/annrheumdis-2012-202846. Epub 2013 Feb 26.
9
Anaemia in inflammatory rheumatic diseases.炎症性风湿性疾病中的贫血。
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10
Effects of a comprehensive intervention program, including hot bathing, on overweight adults: a randomized controlled trial.综合干预方案(包括热水浴)对超重成年人的影响:一项随机对照试验。
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四腕藤疗法治类风湿关节炎相关心脏危险因素红细胞沉降率、血脂谱和致动脉粥样硬化指数的疗效。

Efficacy of Siwan Traditional Therapy on Erythrocyte Sedimentation Rate, Lipid Profile, and Atherogenic Index as Cardiac Risk Factors Related to Rheumatoid Arthritis.

机构信息

Rehabilitation Sciences Department, Health and Rehabilitation Sciences College, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.

Orthopedics and Orthopedic Surgery Department, Physical Therapy Faculty, Ahram Canadian University, Giza P.O. Box 12451, Egypt.

出版信息

Medicina (Kaunas). 2022 Dec 27;59(1):54. doi: 10.3390/medicina59010054.

DOI:10.3390/medicina59010054
PMID:36676677
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9861765/
Abstract

: The most frequent cause of mortality in rheumatoid arthritis (RA) patients is cardiovascular disease (CVD). Inflammation, dyslipidemia, and decreased physical activity are some of the main risk factors for CVD. Siwan sand therapy is a type of traditional therapy used in Egypt to treat RA. The approach of this therapy depends on the experience of the healers. The aim of the current study was to compare the effects of three sessions of Siwan traditional therapy to five sessions on common CVD risk factors and physical function in rheumatoid arthritis patients. Thirty patients (9 male and 21 female) were assigned into two groups of equal size: group (A) received three sessions of Siwan traditional therapy in the form of a sand bath. Group (B) received the same form of therapy for five days. Erythrocyte sedimentation rate (ESR), lipid profile, atherogenic index of plasma (AIP), and a health assessment questionnaire (HAQ) were measured before and after treatment. There was a significant increase above normal within group (A) for ESR ( = 0.001), triglycerides (TG; = 0.015), total cholesterol (Tot-Chol; = 0.0001), and low-density lipoprotein (LDL; = 0.0001). However, there were no considerable differences in high-density lipoprotein (HDL; = 0.106), very low-density lipoprotein (VLDL; = 0.213), AIP ( = 0.648), and HAQ ( = 0.875). For the second group, there were significant changes within group B only in Tot-Chol ( = 0.0001), HDL ( = 0.0001), VLDL ( = 0.0001), AIP ( = 0.008), and HAQ ( = 0.014). There was a significant difference between both groups regarding HDL ( = 0.027), LDL ( = 0.005), AIP ( = 0.029), ESR ( = 0.016), and HAQ ( = 0.036). For RA patients, five days of Siwan traditional therapy caused significant changes regarding inflammation, Tot-Chol, LDL, HDL, AIP, and functional activity when compared to three days of Siwan hot sand therapy.

摘要

类风湿关节炎(RA)患者死亡的最常见原因是心血管疾病(CVD)。炎症、血脂异常和体力活动减少是 CVD 的一些主要危险因素。Siwan 沙疗是埃及用于治疗 RA 的一种传统疗法。这种疗法的方法取决于治疗师的经验。本研究的目的是比较三次 Siwan 传统疗法和五次疗法对类风湿关节炎患者常见 CVD 危险因素和身体功能的影响。

三十名患者(9 名男性和 21 名女性)被分为两组,每组人数相等:组(A)接受三次沙浴形式的 Siwan 传统疗法。组(B)接受相同形式的五天治疗。治疗前后测量红细胞沉降率(ESR)、血脂谱、血浆致动脉粥样硬化指数(AIP)和健康评估问卷(HAQ)。

组内(A)ESR(=0.001)、三酰甘油(TG;=0.015)、总胆固醇(Tot-Chol;=0.0001)和低密度脂蛋白(LDL;=0.0001)均显著升高。然而,高密度脂蛋白(HDL;=0.106)、极低密度脂蛋白(VLDL;=0.213)、AIP(=0.648)和 HAQ(=0.875)无显著差异。对于第二组,仅在组 B 中观察到 Tot-Chol(=0.0001)、HDL(=0.0001)、VLDL(=0.0001)、AIP(=0.008)和 HAQ(=0.014)的显著变化。两组间 HDL(=0.027)、LDL(=0.005)、AIP(=0.029)、ESR(=0.016)和 HAQ(=0.036)存在显著差异。

对于 RA 患者,与三次 Siwan 热沙疗法相比,五天的 Siwan 传统疗法可显著改善炎症、总胆固醇、LDL、HDL、AIP 和功能活动。