College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea.
Medicina (Kaunas). 2023 Jan 12;59(1):151. doi: 10.3390/medicina59010151.
: We aimed to describe medication-related incidents or medication errors (MEs) reported by community pharmacists and analyze the prevalent medications involved. : We extracted ME reports from databases comprising patient safety incidents reported to the Korean Pharmaceutical Association between January 2013 and June 2021. Medications were analyzed according to the second (therapeutic subgroup) and fifth (chemical substance) levels of the Anatomical Therapeutic Chemical classification. : A total of 9046 MEs were identified, most of which were near miss reports (88.3%). Among the errors that reached the patients (521 cases), harmful incidents accounted for 76.8%. Most MEs occurred during prescription (89.5%), while harmful MEs occurred mainly during dispensing (73.3%). In the prescription step, wrong drugs (44.8%), dosing errors (27.0%), and wrong durations (14.0%) were common. Anti-inflammatory and anti-rheumatic products (M01), drugs for acid-related disorders (A02), and antihistamines for systemic use (R06) were the most frequently reported medication classes involved. Harmful incidents were most common for dosing errors (31.0%) and wrong drugs (26.8%) and were common with warfarin, levothyroxine, and glimepiride. : The MEs reported by community pharmacists were mainly prescribing errors, most of which were rectified before reaching patients. The prevalent medications involved in harmful errors include anti-diabetic, anti-thrombotic, and anti-inflammatory agents.
我们旨在描述社区药剂师报告的与药物相关的事件或药物错误（MEs），并分析涉及的常见药物。我们从韩国制药协会报告的患者安全事件数据库中提取 ME 报告，这些报告涵盖 2013 年 1 月至 2021 年 6 月期间。根据药物的解剖治疗化学分类的第二（治疗亚组）和第五（化学物质）级别对药物进行分析。确定了 9046 例 MEs，其中大多数为接近错失报告（88.3%）。在到达患者的错误中（521 例），有害事件占 76.8%。大多数 MEs 发生在处方（89.5%）期间，而有害 MEs 主要发生在配药（73.3%）期间。在处方步骤中，常见的错误包括药物错误（44.8%）、剂量错误（27.0%）和持续时间错误（14.0%）。涉及的最常见药物类别是抗炎和抗风湿产品（M01）、酸相关疾病药物（A02）和全身用抗组胺药（R06）。剂量错误（31.0%）和药物错误（26.8%）最常导致有害事件，华法林、左甲状腺素和格列美脲等药物常见此类错误。社区药剂师报告的 MEs 主要是处方错误，其中大多数在到达患者之前得到纠正。涉及有害错误的常见药物包括抗糖尿病药、抗血栓药和抗炎药。
