Institute of Heart Diseases, University Hospital, 50-566 Wrocław, Poland.
Department of Anaesthesiology and Intensive Care, University Hospital, 50-556 Wrocław, Poland.
Nutrients. 2023 Jan 14;15(2):436. doi: 10.3390/nu15020436.
Contemporarily, cardiac arrest (CA) remains one of the leading causes of death. Poor nutritional status can increase the post-CA mortality risk. The aim of this study was to determine the relationship between body mass index (BMI) and Nutritional Risk Score 2002 (NRS 2002) results and in-hospital mortality in patients admitted to the intensive care unit (ICU) after in-hospital and out-of-hospital cardiac arrest.
A retrospective study and analysis of medical records of 161 patients admitted to the ICU of the University Clinical Hospital in Wrocław (Wrocław, Poland) was conducted.
No significant differences in body mass index (BMI) and nutritional risk score (NRS 2002) values were observed between non-survivors and survivors. Non-survivors had significantly lower albumin concentration ( = 0.017) and total cholesterol (TC) ( = 0.015). In multivariate analysis BMI and NRS 2002 scores were not, per se, associated with the in-hospital mortality defined as the odds of death (Model 1: : 0.700, 0.430; Model 2: : 0.576, 0.599). Univariate analysis revealed significant associations between the hazard ratio (HR) and TG ( ≈ 0.017, HR: 0.23) and hsCRP ( ≈ 0.018, HR: 0.34). In multivariate analysis, mortality risk over time was influenced by higher scores in parameters such as BMI (HR = 0.164; = 0.048) and hsCRP (HR = 1.006, = 0.002).
BMI and NRS 2002, on their own (unconditionally - in the whole study group) did not alter the odds of mortality in patients admitted to the intensive care unit (ICU) after in-hospital and out-of-hospital cardiac arrest. The risk of in-hospital mortality (expressed as hazard ratio - the risk over the time period of the study) increased with an increase in BMI but not with NRS 2002.
目前，心脏骤停（CA）仍然是导致死亡的主要原因之一。较差的营养状况会增加 CA 后死亡的风险。本研究旨在确定身体质量指数（BMI）和营养风险评分 2002（NRS 2002）结果与院内和院外心脏骤停后入住重症监护病房（ICU）的患者院内死亡率之间的关系。
对波兰弗罗茨瓦夫大学临床医院（Wrocław，波兰） ICU 收治的 161 例患者进行回顾性研究和病历分析。
幸存者和非幸存者之间的 BMI 和 NRS 2002 值无显著差异。非幸存者的白蛋白浓度（ = 0.017）和总胆固醇（TC）（ = 0.015）明显较低。多变量分析中，BMI 和 NRS 2002 评分本身与院内死亡率（定义为死亡的几率）无关（模型 1：比值比（OR）= 0.700，95%置信区间（CI）= 0.430；模型 2：OR = 0.576，95%CI = 0.599）。单变量分析显示，TG（ ≈ 0.017，HR = 0.23）和 hsCRP（ ≈ 0.018，HR = 0.34）与危险比（HR）之间存在显著关联。多变量分析中，随着 BMI（HR = 0.164； = 0.048）和 hsCRP（HR = 1.006， = 0.002）等参数评分的升高，死亡率随时间的变化而增加。
BMI 和 NRS 2002 单独（无条件地-在整个研究组中）并未改变院内和院外心脏骤停后入住 ICU 的患者的死亡率几率。住院死亡率的风险（以危险比表示-研究期间的风险）随着 BMI 的增加而增加，但与 NRS 2002 无关。
