Nassar Razan I, Barakat Muna, Thiab Samar, El-Hajji Feras, Barqawi Hiba, El-Huneidi Waseem, Basheti Iman A, Abu-Gharbieh Eman
Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman 11931, Jordan.
Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmacy, Applied Science Private University, Amman 11931, Jordan.
Vaccines (Basel). 2022 Dec 25;11(1):44. doi: 10.3390/vaccines11010044.
The perception of COVID-19 vaccines as being unsafe is a major barrier to receiving the vaccine. Providing the public with accurate data regarding the vaccines would reduce vaccine hesitancy.
A cross-sectional study was conducted to collect data on the side effects experienced by the vaccinated population to assess the safety of the inactivated COVID-19 vaccine.
The majority of the study participants (n = 386) were female (71.9%), and 38.6% of them were under 30 years old. Around half of the participants (52.8%) reported side effects after receiving the inactivated COVID-19 vaccine. Fatigue (85.1%), a sore arm at the site of the injection (82.1%), and discomfort (67.2%) were the most commonly reported side effects after the first dose. Reporting side effects was significantly associated with the female sex (-value = 0.027). Significant associations between being female and experiencing chills, muscle or joint pain, anorexia, drowsiness, and hair loss were also found, as well as being above the age of 30 and experiencing a cough. Being a smoker was significantly associated with experiencing a cough, and a headache. Furthermore, chills, and a sore throat were significantly associated with individuals who had not been infected before.
Mild side effects were reported after receiving the inactivated COVID-19 vaccine. Fatigue was the most commonly reported side effect. Females, older adults, smokers, and those who had never been infected with COVID-19 had a greater susceptibility to certain side effects.
认为新冠病毒疫苗不安全是接种疫苗的一个主要障碍。向公众提供有关疫苗的准确数据将减少疫苗犹豫情绪。
开展了一项横断面研究，收集接种人群经历的副作用数据，以评估新冠病毒灭活疫苗的安全性。
大多数研究参与者（n = 386）为女性（71.9%），其中38.6%年龄在30岁以下。约一半参与者（52.8%）报告在接种新冠病毒灭活疫苗后出现副作用。疲劳（85.1%）、注射部位手臂酸痛（82.1%）和不适（67.2%）是首剂接种后最常报告的副作用。报告副作用与女性显著相关（P值 = 0.027）。还发现女性与出现寒战、肌肉或关节疼痛、厌食、嗜睡和脱发之间存在显著关联，以及30岁以上与出现咳嗽之间存在显著关联。吸烟者与出现咳嗽和头痛显著相关。此外，寒战和喉咙痛与既往未感染过的个体显著相关。
接种新冠病毒灭活疫苗后报告了轻微副作用。疲劳是最常报告的副作用。女性、老年人、吸烟者以及从未感染过新冠病毒的人对某些副作用更为敏感。
