一只狗患嗜碱性粒细胞白血病。

Basophilic leukaemia in a dog.

作者信息

Mahaffey E A, Brown T P, Duncan J R, Latimer K S, Brown S A

机构信息

Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens 30602.

出版信息

J Comp Pathol. 1987 Jul;97(4):393-9. doi: 10.1016/0021-9975(87)90017-x.

DOI:10.1016/0021-9975(87)90017-x

PMID:3667995

Abstract

Leukaemia in an 11-year-old bitch was characterized by the presence in the peripheral blood and bone marrow of cells with lobulated nuclei and numerous metachromatic cytoplasmic granules. The results of cytochemical stains for peroxidase and naphthol AS-D chloracetate esterase activity were negative. Ultrastructurally, the cytoplasmic granules were finely granular with no membranous coils or crystalline lattice structures. Based on these findings, the neoplastic cells were classified as basophils.

摘要

一只11岁母犬患白血病，其特征是外周血和骨髓中存在核呈分叶状且有大量异染性胞质颗粒的细胞。过氧化物酶和萘酚AS-D氯乙酸酯酶活性的细胞化学染色结果为阴性。超微结构上，胞质颗粒为细颗粒状，无膜性螺旋或晶格结构。基于这些发现，肿瘤细胞被分类为嗜碱性粒细胞。