Skopińska E
Transplantation. 1978 Dec;26(6):420-2.
Lipopolysaccharide (LPS) from Escherichia coli administered to allografted mice in a single dose of 20 microgram influenced the development of cell-mediated immunity to skin donor antigens. As an indicator of cell-mediated immunity, donor antigen-induced inhibition of cell migration from spleen explants of allografted animals was used. Cultures of spleen explants were established 16 days after grafting. The antigen-specific inhibition of migration was abolished when LPS was injected either 4 to 2 days before grafting and intensified when LPS was administered on the 2nd day after grafting.
以单剂量20微克给同种异体移植小鼠注射来自大肠杆菌的脂多糖（LPS），会影响对皮肤供体抗原的细胞介导免疫的发展。作为细胞介导免疫的指标，使用供体抗原诱导的同种异体移植动物脾外植体细胞迁移抑制。移植后16天建立脾外植体培养物。当在移植前4至2天注射LPS时，迁移的抗原特异性抑制被消除，而当在移植后第2天给予LPS时，这种抑制会增强。
