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老年痴呆症新诊断患者的住院情况:以色列一项基于人群的纵向研究。

Hospitalizations in older-adults newly diagnosed with dementia: A population-based longitudinal study in Israel.

机构信息

The Israel Center for Disease Control, Ministry of Health, Ramat Gan, Israel.

Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.

出版信息

Int J Geriatr Psychiatry. 2023 Jan;38(1):e5871. doi: 10.1002/gps.5871.

Abstract

OBJECTIVES

To compare inpatient burden (i.e. likelihood of hospitalization, number of admissions and length of stay) in persons with newly diagnosed dementia to the general population without dementia. Additionally, to evaluate whether inpatient burden is increased during the years prior to and post dementia diagnosis, and to identify factors associated with increased inpatient burden.

METHOD

The Israeli National Dementia Dataset (2016) was cross-linked with the National Hospital Discharge Database of the Israeli Ministry of Health (2014-2018). Dementia definition was based on documented dementia diagnoses and/or the purchase of medications during 2016. Mixed-effects models were applied to identify demographic and health characteristics associated with inpatient burden in the one and 2 years prior to and after dementia diagnosis.

RESULTS

The dataset included 11,625 individuals aged ≥65 years, identified as incident dementia cases. Compared to the general population of older-adults without dementia, those with newly diagnosed dementia had a higher age-standardized proportion of hospitalizations (26.4% vs. 40%). The odds for hospitalization were highest during the year preceding dementia diagnosis (OR = 3.19, 95% CI 2.51-4.06) compared to 2 years prior to diagnosis, and remained high (although slightly decreased) after dementia diagnosis. Older age was associated with inpatient burden after, but not prior to dementia diagnosis.

CONCLUSIONS

Older persons with dementia are a vulnerable population group with increased utilization of inpatient burden compared to those without dementia, particularly in the years surrounding dementia diagnosis. Sociodemographic risk factors may differ with respect to the time surrounding dementia diagnosis.

摘要

目的

比较新诊断痴呆患者与无痴呆的普通人群的住院负担(即住院可能性、住院次数和住院时间)。此外,评估痴呆诊断前和后几年的住院负担是否增加,并确定与住院负担增加相关的因素。

方法

以色列国家痴呆数据集(2016 年)与以色列卫生部国家住院数据库(2014-2018 年)进行了交叉链接。痴呆的定义基于 2016 年记录的痴呆诊断和/或购买药物的情况。应用混合效应模型来确定与痴呆诊断前 1 年和后 2 年住院负担相关的人口统计学和健康特征。

结果

数据集包括 11625 名年龄≥65 岁的新诊断痴呆患者。与无痴呆的普通老年人群相比,新诊断痴呆患者的住院比例标准化更高(26.4%比 40%)。在痴呆诊断前一年,住院的可能性最高(OR=3.19,95%CI 2.51-4.06),与诊断前 2 年相比更高,并且在痴呆诊断后仍然较高(尽管略有下降)。年龄较大与痴呆诊断后而非前的住院负担相关。

结论

与无痴呆者相比,痴呆老年人是一个脆弱的人群群体,住院负担增加,尤其是在痴呆诊断前后的几年。痴呆诊断前后的社会人口学危险因素可能不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e1/10108175/9813cb5b7e50/GPS-38-0-g002.jpg

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