Wu Qinrui, Li Zhengyi, Zhang Yixin, Peng Xian, Zhou Xuedong
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Front Pediatr. 2023 Jan 4;10:1092809. doi: 10.3389/fped.2022.1092809. eCollection 2022.
Cleft lip and palate (CLP) is the most common congenital facial malformation and has a significant developmental, physical, and psychological impact on those with the deformity and their families. Risk factors contributing to CLP may conclude as genetic factors and environmental factors. The anatomical and morphological abnormalities related to CLP are favorable for dental plaque accumulation on the tooth surface. Therefore, patients with CLP undergo poorer oral hygiene and higher susceptibility to dental caries and periodontitis. In this review, we aim to conclude and update probable causes underlying the association between CLP and poor oral health and provide novel ideas of targeted early prevention for such oral diseases.
唇腭裂(CLP)是最常见的先天性面部畸形,对畸形患者及其家庭产生重大的发育、身体和心理影响。导致唇腭裂的风险因素可能包括遗传因素和环境因素。与唇腭裂相关的解剖学和形态学异常有利于牙菌斑在牙齿表面的积聚。因此,唇腭裂患者的口腔卫生较差,患龋齿和牙周炎的易感性较高。在本综述中,我们旨在总结和更新唇腭裂与口腔健康不良之间关联的潜在可能原因,并为这类口腔疾病提供有针对性的早期预防新思路。