香根草油及其成分对（此处原文未完整给出具体物种名称）、（斯库斯）和（赛伊）的行为回避和生物安全性

Behavioral avoidance and biological safety of vetiver oil and its constituents against (L.), (Skuse) and Say.

作者信息

Nararak Jirod, Giorgio Carole Di, Thanispong Kanutcharee, Sukkanon Chutipong, Sanguanpong Unchalee, Mahiou-Leddet Valerie, Ollivier Evelyne, Chareonviriyaphap Theeraphap, Manguin Sylvie

机构信息

Department of Entomology, Faculty of Agriculture, Kasetsart University, Bangkok 10900, Thailand.

HSM, University of Montpellier, CNRS, IRD, Montpellier, France.

出版信息

Curr Res Insect Sci. 2022 Aug 6;2:100044. doi: 10.1016/j.cris.2022.100044. eCollection 2022.

DOI:10.1016/j.cris.2022.100044

PMID:36683957

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9846461/

Abstract

Numerous plant-based repellents are widely used for personal protection against host-seeking mosquitoes. (L.) Nash essential oil and its constituents have demonstrated various mosquito repellent activities. In this study, three chemical actions of vetiver oil and five constituents (terpinen-4-ol, α-terpineol, valencene, vetiverol and vetivone) were characterized against and by using the high-throughput screening assay system (HITSS). Significant contact escape responses in and to all test compounds at concentrations between 2.5 and 5% were observed. Spatial repellency responses were also observed in some tested mosquito populations depending upon concentrations. The most significant toxic response on mosquitoes was found at the highest concentration, except for vetivone which had no toxic effect on and . Results on phototoxic and genotoxic hazard revealed that vetiver oil and their constituents showed no phototoxic potential or any significant genotoxic response. In conclusion, vetiver oil and two constituents, valencene and vetiverol, are potentials as active ingredients for mosquito repellency and present no toxicity.

摘要

许多植物性驱避剂被广泛用于个人防护，以抵御寻找宿主的蚊子。(L.)纳什香根草精油及其成分已表现出多种驱蚊活性。在本研究中，通过使用高通量筛选分析系统（HITSS），对香根草油的三种化学作用以及五种成分（萜品-4-醇、α-萜品醇、瓦伦烯、香根草醇和香根草酮）针对[具体蚊虫名称1]和[具体蚊虫名称2]进行了表征。在2.5%至5%的浓度下，观察到[具体蚊虫名称1]和[具体蚊虫名称2]对所有测试化合物都有显著的接触逃逸反应。根据浓度不同，在一些受试蚊虫种群中也观察到了空间驱避反应。除香根草酮对[具体蚊虫名称1]和[具体蚊虫名称2]没有毒性作用外，在最高浓度下对蚊子的毒性反应最为显著。光毒性和遗传毒性危害结果表明，香根草油及其成分没有光毒性潜力或任何显著的遗传毒性反应。总之，香根草油以及两种成分瓦伦烯和香根草醇有潜力作为驱蚊活性成分，且无毒性。