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使用安非他酮后消退的露阴癖症状:一例报告。

Symptoms of exhibitionism that regress with bupropion: A case report.

作者信息

Vayısoğlu Sefa

机构信息

Independent Researcher, Adana, Turkey.

出版信息

Front Psychiatry. 2023 Jan 4;13:1079863. doi: 10.3389/fpsyt.2022.1079863. eCollection 2022.

DOI:10.3389/fpsyt.2022.1079863
PMID:36684014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9846203/
Abstract

Exhibitionistic Disorder, one of the paraphilic disorders, is a disease with an unknown etiology and causes significant distress and loss of function in the patient's life. Serotonergic antidepressants are generally preferred in the treatment of this Disorder. However, in this case, we report a patient who did not respond to serotonergic antidepressants but bupropion, an antidepressant with dopaminergic and noradrenergic activity. Therefore, bupropion should be considered a medical treatment alternative in case serotonergic antidepressants do not work efficiently in the treatment of Exhibitionism.

摘要

露阴障碍是性偏好障碍之一,是一种病因不明的疾病,会给患者生活带来极大痛苦并导致功能丧失。在这种障碍的治疗中,通常首选5-羟色胺能抗抑郁药。然而,在此病例中,我们报告了一名对5-羟色胺能抗抑郁药无反应,但对具有多巴胺能和去甲肾上腺素能活性的抗抑郁药安非他酮有反应的患者。因此,在露阴癖治疗中,如果5-羟色胺能抗抑郁药治疗效果不佳,应考虑将安非他酮作为一种治疗选择。

相似文献

1
Symptoms of exhibitionism that regress with bupropion: A case report.使用安非他酮后消退的露阴癖症状:一例报告。
Front Psychiatry. 2023 Jan 4;13:1079863. doi: 10.3389/fpsyt.2022.1079863. eCollection 2022.
2
A case of familial exhibitionism in Tourette's syndrome successfully treated with haloperidol.1例妥瑞氏综合征伴发的家族性露阴癖经氟哌啶醇治疗成功。
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Preferential rape in the theory of courtship disorder.求爱障碍理论中的偏好性强奸
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Fatigue as a core symptom in major depressive disorder: overview and the role of bupropion.疲劳作为重度抑郁症的核心症状:概述及安非他酮的作用
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Bupropion: a review of its mechanism of antidepressant activity.安非他酮:其抗抑郁活性机制综述
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Serotonergic antidepressants decrease hedonic signals but leave learning signals in the nucleus accumbens unaffected.血清素能抗抑郁药会降低享乐信号,但伏隔核中的学习信号不受影响。
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引用本文的文献

1
Pharmacological Interventions in Paraphilic Disorders: Systematic Review and Insights.性偏好障碍的药物干预:系统评价与见解
J Clin Med. 2024 Mar 7;13(6):1524. doi: 10.3390/jcm13061524.

本文引用的文献

1
[Neurotransmitter mechanisms of paraphilic disorders].[性偏好障碍的神经递质机制]
Zh Nevrol Psikhiatr Im S S Korsakova. 2019;119(8):61-67. doi: 10.17116/jnevro201911908161.
2
Drug treatment of paraphilic and nonparaphilic sexual disorders.性偏好障碍和非性偏好性性功能障碍的药物治疗。
Clin Ther. 2009 Jan;31(1):1-31. doi: 10.1016/j.clinthera.2009.01.009.
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Exhibitionism and low-dose trazodone treatment.露阴癖与低剂量曲唑酮治疗
Hum Psychopharmacol. 2000 Jul;15(5):347-349. doi: 10.1002/1099-1077(200007)15:5<347::AID-HUP203>3.0.CO;2-S.
4
Compulsive voyeurism and exhibitionism: a clinical response to paroxetine.强迫性窥阴癖和暴露癖:帕罗西汀的临床疗效
Arch Sex Behav. 1999 Feb;28(1):23-30. doi: 10.1023/a:1018737504537.
5
Exhibitionism treated with clomipramine.用氯米帕明治疗露阴癖。
Am J Psychiatry. 1993 Aug;150(8):1274. doi: 10.1176/ajp.150.8.1274c.
6
Exhibitionism treated with clomipramine.用氯米帕明治疗露阴癖。
Am J Psychiatry. 1993 Aug;150(8):1273-4. doi: 10.1176/ajp.150.8.1273b.
7
Compulsive exhibitionism successfully treated with fluvoxamine: a controlled case study.氟伏沙明成功治疗强迫性露阴癖:一项对照病例研究。
J Clin Psychiatry. 1994 Mar;55(3):86-8.
8
Fluoxetine treatment of exhibitionism.氟西汀治疗露阴癖。
Am J Psychiatry. 1990 Aug;147(8):1089-90. doi: 10.1176/ajp.147.8.1089c.
9
Three cases of paraphilias responsive to fluoxetine treatment.三例对氟西汀治疗有反应的性偏好障碍病例。
J Clin Psychiatry. 1991 Apr;52(4):169-70.
10
Clomipramine and a case of exhibitionism.氯米帕明与一例露阴癖病例。
Am J Psychiatry. 1992 Jun;149(6):843. doi: 10.1176/ajp.149.6.843a.