Abouesh A, Clayton A
Arch Sex Behav. 1999 Feb;28(1):23-30. doi: 10.1023/a:1018737504537.
The compulsive behaviors seen in sexual paraphilias may be related to those of obsessive-compulsive disorder (OCD). Based primarily upon case reports as well as studies indicating the effectiveness of serotonin reuptake inhibitors in the treatment of sexual paraphilias, it has been speculated that sexual paraphilias lie within the obsessive-compulsive spectrum. There have been no reports of the use of paroxetine in the treatment of sexual paraphilias. This is a report of two patients, the first a voyeur and the second an exhibitionist, both of whom responded to treatment with paroxetine. The discussion addresses the need for further comparative studies investigating the role of the serotonin system in the pathogenesis of sexual paraphilias and OCD as well as the effect of serotonin reuptake inhibitors in comparison to other pharmacologic modalities used in the treatment of paraphilias.
性偏好障碍中出现的强迫行为可能与强迫症（OCD）的强迫行为有关。主要基于病例报告以及表明5-羟色胺再摄取抑制剂在治疗性偏好障碍方面有效性的研究，有人推测性偏好障碍属于强迫谱系。尚无使用帕罗西汀治疗性偏好障碍的报告。本文报告了两名患者，第一名是窥阴癖者，第二名是露阴癖者，两人均对帕罗西汀治疗有反应。讨论涉及开展进一步比较研究的必要性，这些研究旨在调查5-羟色胺系统在性偏好障碍和强迫症发病机制中的作用，以及5-羟色胺再摄取抑制剂与用于治疗性偏好障碍的其他药物治疗方式相比的效果。
