Morris J, Barker D J, Nelson M
MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital.
J Epidemiol Community Health. 1987 Mar;41(1):44-9. doi: 10.1136/jech.41.1.44.
During 1979-82 hospital discharge rates after emergency admission for acute appendicitis were higher in Eire (17.4 per 10,000 population) than in England (10.3), Scotland (11.1), or Wales (12.3). Comparison of food consumption between the four countries, and between the health board areas of Eire and regions of Scotland, shows that appendicitis rates are highest in communities that consume more potatoes, sugar, and cereals, and less non-potato vegetables and fruit. The rates are also related to mortality from enteric and respiratory infections, to general practice consultations for infective disease, and to postneonatal mortality. This is evidence in favour of the hygiene hypothesis for the aetiology of appendicitis.
1979年至1982年期间，爱尔兰急性阑尾炎急诊入院后的医院出院率（每10000人口中有17.4人）高于英格兰（10.3）、苏格兰（11.1）或威尔士（12.3）。对这四个国家之间，以及爱尔兰的健康委员会地区与苏格兰各地区之间的食物消费情况进行比较后发现，阑尾炎发病率在食用较多土豆、糖和谷物，而食用较少非土豆类蔬菜和水果的社区中最高。这些发病率还与肠道和呼吸道感染的死亡率、传染病的全科诊疗咨询以及新生儿后期死亡率有关。这为阑尾炎病因的卫生假说提供了证据。
