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急性阑尾炎与膳食纤维：一种替代性假说。

Acute appendicitis and dietary fibre: an alternative hypothesis.

作者信息

Barker D J

出版信息

Br Med J (Clin Res Ed). 1985 Apr 13;290(6475):1125-7. doi: 10.1136/bmj.290.6475.1125.

DOI:10.1136/bmj.290.6475.1125
PMID:2985169
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1418708/
Abstract

This paper examines the time trends in acute appendicitis in Britain in relation to changes in consumption of fibre, meat, and sugar. Knowledge of previous case fatality rates, diagnostic criteria, and management are sufficient to infer general trends in incidence from mortality data. The incidence rose steeply from around 1895 and fell from the 1930s onwards. Contrary to previous statements there is no evidence that disease rates were greatly influenced by the dietary changes in the second world war. It is concluded that dietary changes do not explain the time trends in appendicitis and that the epidemiology of the disease is more readily explained by a primarily infectious aetiology.

摘要

本文研究了英国急性阑尾炎的时间趋势，及其与纤维、肉类和糖消费量变化的关系。了解既往的病死率、诊断标准和治疗方法，足以从死亡率数据推断出发病率的总体趋势。发病率从1895年左右开始急剧上升，并从20世纪30年代起开始下降。与之前的说法相反，没有证据表明第二次世界大战期间的饮食变化对发病率有很大影响。研究得出结论，饮食变化无法解释阑尾炎的时间趋势，而该疾病的流行病学更易于用主要的感染病因来解释。

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本文引用的文献

1
Aetiology of Appendicitis.阑尾炎的病因
Br Med J. 1938 Jan 29;1(4021):227-30. doi: 10.1136/bmj.1.4021.227.
2
Historic Phases of Appendicitis.阑尾炎的历史阶段
Ann Surg. 1931 Aug;94(2):179-96. doi: 10.1097/00000658-193108000-00003.
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Is appendicitis decreasing in frequency.阑尾炎的发病率在下降吗？
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The falling incidence of appendicitis.阑尾炎发病率的下降。
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The role of Bacteroides fragilis in the pathogenesis of acute appendicitis.脆弱拟杆菌在急性阑尾炎发病机制中的作用。
Acta Chir Scand. 1982;148(1):39-44.
6
Acute appendicitis and dietary fiber.急性阑尾炎与膳食纤维
Arch Surg. 1983 Jul;118(7):868-70. doi: 10.1001/archsurg.1983.01390070076015.
7
Decreasing incidence of acute appendicitis, with special reference to the consumption of dietary fiber.
Acta Chir Scand. 1982;148(5):461-4.
8
Dietary fibre and acute appendicitis: a case-control study.膳食纤维与急性阑尾炎：一项病例对照研究。
Hum Nutr Appl Nutr. 1984 Apr;38(2):126-31.
9
Trends in food consumption in the United Kingdom.
World Rev Nutr Diet. 1966;6:34-89. doi: 10.1159/000391422.
10
The aetiology of appendicitis.阑尾炎的病因。
Br J Surg. 1971 Sep;58(9):695-9. doi: 10.1002/bjs.1800580916.