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蘑菇中毒患者的死亡率与肝移植:一项系统评价与荟萃分析

Mortality rate and liver transplant in patients with mushroom poisoning: A systematic review & meta-analysis.

作者信息

Janatolmakan Maryam, Jalilian Milad, Rezaeian Shahab, Abdi Alireza, Khatony Alireza

机构信息

Social Development and Health Promotion Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Heliyon. 2022 Dec 30;9(1):e12759. doi: 10.1016/j.heliyon.2022.e12759. eCollection 2023 Jan.

Abstract

BACKGROUND

Mushroom poisoning is raised as a poor food problem that can cause the death of patients or the need for a liver transplant.

OBJECTIVE

This study was conducted with the aim of assessment the mortality rate and liver transplantation in people suffering from mushroom poisoning through a systematic review and meta-analysis.

METHOD

The study is designed and conducted based on the PRISMA statement. International databases have been checked for articles up to March 1, 2022. The results of the study are presented with the guidance of Garrard's statement. CMA software was used in meta-analysis.

RESULTS

Thirty-three articles were selected for this study. The mortality rate reported 0-40% and the results of the meta-analysis showed that the mortality rate was 2.87%. in other hand the mortality rate was 1.4% with studies that reported zero death. Overall, 16 patients had liver transplants, that only 2 died after liver transplants and 14 others survived.

CONCLUSION

The death in patients with mushroom poisoning is significant. Patients with liver disorders and patients or kidney disorders are more likely to have a poor prognosis. Liver transplant can be lifesaving. Also, quick referral of patients in the early stages reduces the need for liver transplantation.

摘要

背景

蘑菇中毒作为一个严重的食品安全问题被提出,它可能导致患者死亡或需要进行肝移植。

目的

本研究旨在通过系统评价和荟萃分析评估蘑菇中毒患者的死亡率和肝移植情况。

方法

本研究依据PRISMA声明进行设计和实施。检索了截至2022年3月1日的国际数据库中的相关文章。研究结果依据Garrard声明进行呈现。荟萃分析使用CMA软件。

结果

本研究选取了33篇文章。报道的死亡率为0 - 40%,荟萃分析结果显示死亡率为2.87%。另一方面,在报告零死亡的研究中死亡率为1.4%。总体而言,16例患者接受了肝移植,其中仅2例在肝移植后死亡,其他14例存活。

结论

蘑菇中毒患者的死亡情况较为严重。患有肝脏疾病、肾脏疾病的患者预后较差。肝移植可挽救生命。此外,在早期快速转诊患者可减少肝移植需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04fe/9849942/e10eeb641309/gr1.jpg

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