化脓性汗腺炎：外科治疗中的细菌学研究
Hidradenitis suppurativa: bacteriological study in surgical treatment.
作者信息
Gierek Marcin, Ochała-Gierek Gabriela, Kitala Diana, Łabuś Wojciech, Bergler-Czop Beata
机构信息
Dr Sakiel's Centre for Burn Treatment, Siemianowice Śląskie, Poland.
Department of Dermatology and Venereology, Sosnowiec City Hospital, Sosnowiec, Poland.
出版信息
Postepy Dermatol Alergol. 2022 Dec;39(6):1101-1105. doi: 10.5114/ada.2022.119008. Epub 2022 Sep 9.
Abstract
INTRODUCTION
Hidradenitis suppurativa (HS) is an inflammatory chronic disease of the hair follicles that presents with different lesions in the apocrine gland-bearing areas of the human body. There are many possible factors for HS. Acne inversa is not primarily considered to be an infectious disease. A variety of Gram-positive and Gram-negative bacteria have been found from the lesions sporadically.
AIM
To assess the bacteriological profile of HS before surgical treatment.
MATERIAL AND METHODS
We collected specimens for aerobic microbiological testing from 18 patients before surgical treatment in our hospital. The specimens were obtained from abscesses, directly from skin fistulas, on day 1 of hospitalisation.
RESULTS
The most common bacteria in HS lesions were Staphylococcus aureus and Proteus mirabilis. In 4 patients we found multi-drug-resistant bacteria (MLSB, MRSA and A. baumannii).
CONCLUSIONS
Long-term antibiotic treatment can cause multi-drug resistance in strains collected in HS lesions.
摘要
引言
化脓性汗腺炎（HS）是一种毛囊的炎症性慢性疾病，在人体含有顶泌汗腺的区域表现为不同的皮损。HS存在多种可能的因素。反向痤疮主要不被认为是一种传染病。已偶尔从皮损中发现多种革兰氏阳性菌和革兰氏阴性菌。
目的
评估手术治疗前HS的细菌学特征。
材料与方法
我们收集了我院18例手术治疗前患者的标本进行需氧微生物检测。标本于住院第1天从脓肿、直接从皮肤瘘管获取。
结果
HS皮损中最常见的细菌是金黄色葡萄球菌和奇异变形杆菌。在4例患者中我们发现了多重耐药菌（大环内酯类耐药性、耐甲氧西林金黄色葡萄球菌和鲍曼不动杆菌）。
结论
长期抗生素治疗可导致HS皮损中分离出的菌株产生多重耐药性。
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本文引用的文献
1
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Antibiotics (Basel). 2021 Nov 17;10(11):1406. doi: 10.3390/antibiotics10111406.
2
Hidradenitis suppurativa.化脓性汗腺炎。
Nat Rev Dis Primers. 2020 Mar 12;6(1):18. doi: 10.1038/s41572-020-0149-1.
3
Human Microbiome: Composition and Role in Inflammatory Skin Diseases.人类微生物组：组成与在炎症性皮肤疾病中的作用。
Arch Immunol Ther Exp (Warsz). 2019 Feb;67(1):1-18. doi: 10.1007/s00005-018-0528-4. Epub 2018 Oct 9.
4
Oral ofloxacin and clindamycin as an alternative to the classic rifampicin-clindamycin in hidradenitis suppurativa: retrospective analysis of 65 patients.口服氧氟沙星和克林霉素替代经典的利福平-克林霉素治疗化脓性汗腺炎：65例患者的回顾性分析
Br J Dermatol. 2018 Jan;178(1):e15-e16. doi: 10.1111/bjd.15739. Epub 2017 Dec 7.
5
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J Eur Acad Dermatol Venereol. 2017 Nov;31(11):1800-1808. doi: 10.1111/jdv.14345. Epub 2017 Jun 7.
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Front Cell Infect Microbiol. 2017 Mar 13;7:55. doi: 10.3389/fcimb.2017.00055. eCollection 2017.
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8
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10
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