Hamano Tadanori, Nagata Miwako, Matsubara Rokuro, Ikebata Yukihiko, Ito Tatsuhiko, Ibe Akihiro, Fujita Youshi, Kusaka Yukinori, Tokunaga Takahiro, Enomoto Soichi, Endo Yoshinori, Ueno Asako, Shirafuji Norimichi, Ikawa Masamichi, Hayashi Kouji, Yamamura Osamu, Nakamoto Yasunari
Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Department of Aging and Dementia (DAD), Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Front Aging Neurosci. 2023 Jan 4;14:1029614. doi: 10.3389/fnagi.2022.1029614. eCollection 2022.
Early intervention for dementia patients is extremely important for the prevention of dementia. However, so far, it is not clear as to what kind of screening will be useful for the early detection of dementia. We aimed to investigate the relationship between the results of a short self-reporting yes/no survey selected in Kihon Checklist, developed by the Japanese Ministry of Health, Labor and Welfare to identify older adults who are at risk of requiring support/care, and other original items developed by Dementia Prevention Team, Fukui, Japan, and Mini-Mental State Examination (MMSE) scores, and determine the diagnostic efficacy of the self-reporting yes/no survey. Self-reporting yes/no surveys were conducted for 87,687 individuals aged ≥65 years, living in Fukui, Japan, and did not have Long-Term Care Insurance, Japan. According to the survey results, selected individuals were advised to visit a local hospital to be assessed with MMSE. Individuals who could not make a call by looking up phone numbers and manage their own deposits and savings at the bank or automatic teller machine (ATM) had an increased risk of low MMSE score (≤23; odds ratio: 2.74 [1.89-3.97]; 95% confidence interval: 2.12 [1.46-3.07]). Self-reporting yes/no survey could effectively screen for dementia. Not being able to make a call by looking up phone numbers and not being able to manage their own deposits and savings at the bank or ATM are signs of dementia.
对痴呆症患者进行早期干预对于预防痴呆症极为重要。然而，到目前为止，尚不清楚哪种筛查方法对早期发现痴呆症有用。我们旨在研究日本厚生劳动省制定的用于识别有需要支持/护理风险的老年人的《基準チェックリスト》中所选的简短自我报告是/否调查结果、日本福井痴呆症预防团队制定的其他原始项目以及简易精神状态检查表（MMSE）评分之间的关系，并确定自我报告是/否调查的诊断效力。对居住在日本福井、年龄≥65岁且没有日本长期护理保险的87,687人进行了自我报告是/否调查。根据调查结果，建议被选中的人前往当地医院接受MMSE评估。无法通过查找电话号码拨打电话以及无法在银行或自动取款机（ATM）管理自己的存款和储蓄的人，其MMSE得分较低（≤23）的风险增加（优势比：2.74 [1.89 - 3.97]；95%置信区间：2.12 [1.46 - 3.07]）。自我报告是/否调查可以有效地筛查痴呆症。无法通过查找电话号码拨打电话以及无法在银行或ATM管理自己的存款和储蓄是痴呆症的迹象。
