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定制颌骨植入物联合游离腓骨瓣进行全下颌骨及双侧颞下颌关节重建:病例报告及文献综述

Total mandible and bilateral TMJ reconstruction combining a customized jaw implant with a free fibular flap: a case report and literature review.

作者信息

Govoni Flavio Andrea, Felici Nicola, Ornelli Matteo, Marcelli Vincenzo Antonio, Migliano Emilia, Pesucci Bruno Andrea, Pistilli Roberto

机构信息

Unit of Maxillofacial Surgery, San Camillo-Forlanini Hospital, Rome, Italy.

Unit of Plastic and Reconstructive Surgery of the Limbs, San Camillo-Forlanini Hospital, Rome, Italy.

出版信息

Maxillofac Plast Reconstr Surg. 2023 Jan 23;45(1):6. doi: 10.1186/s40902-023-00374-w.

Abstract

BACKGROUND

The need for whole mandibular bone reconstruction and bilateral joint replacement is fortunately rare, but it is an extremely challenging topic in maxillofacial surgery, due to its functional implications. CAD-CAM techniques development has opened new broad horizons in the surgical planning of complex maxillofacial reconstructions, in terms of accuracy, predictability, and functional cosmetic results. The review of the literature has revealed a small number of scientific reports on total mandibulectomy including the condyles, with only eleven cases from 1980. Most of the works describe reconstructions secondary to dysplastic or inflammatory diseases affecting the lower jaw. The aim of this work, reporting a rare case of massive fibrous dysplasia of the whole mandible, is to share our experience in the management of extended mandibular and bilateral joint reconstruction, using porous titanium patient-specific implants.

CASE PRESENTATION

The authors present a 20-year-old male patient suffering from massive bone fibrous dysplasia of the mandible. The mandibular body and both the rami and the condylar processes had been involved, causing severe functional impairment, tooth loss, and facial deformation. The young patient, after repeated ineffective conservative surgical treatments, has required a biarticular mandibular replacement. Using virtual surgical planning (VSP) software, the authors, in collaboration with medical engineers, have created a custom-made original titanium porous mandibular implant, suspended from a bilateral artificial temporomandibular joint. The mandibular titanium implant body has been specifically designed to support soft tissues and to fix, in the alveolar region, a free fibular bone graft, for delayed dental implant prosthetic rehabilitation.

CONCLUSION

The surgical and technical details, as well as the new trends in mandibular reconstructions using porous titanium implants, are reported, and discussed, reviewing literature reports on this topic. Satisfactory functional and cosmetic restorative results have been obtained, and no major complications have occurred. The patient, currently in the 18 month clinical and radiological follow-up, has recently completed the functional restoration program by an implant-supported full-arch dental prosthesis.

摘要

背景

全下颌骨重建及双侧关节置换的需求所幸较为罕见,但因其功能影响,在颌面外科领域是极具挑战性的课题。计算机辅助设计与制造(CAD - CAM)技术的发展在复杂颌面重建手术规划方面,在准确性、可预测性及功能美容效果上开辟了新的广阔前景。文献回顾显示,关于包括髁突在内的全下颌骨切除术的科学报告数量较少,自1980年仅有11例。大多数研究描述的是继发于影响下颌骨的发育异常或炎性疾病后的重建。本文报告一例罕见的全下颌骨巨大纤维性发育异常病例,目的是分享我们使用多孔钛定制植入物进行下颌骨延长及双侧关节重建的经验。

病例报告

作者介绍一名20岁男性患者,患有下颌骨巨大骨纤维性发育异常。下颌骨体、升支及髁突均受累,导致严重功能障碍、牙齿缺失及面部畸形。该年轻患者在多次保守手术治疗无效后,需要进行双关节下颌置换。作者与医学工程师合作,使用虚拟手术规划(VSP)软件制作了定制的原创多孔钛下颌植入物,其由双侧人工颞下颌关节悬吊。下颌钛植入物主体经过专门设计,以支撑软组织,并在牙槽区域固定游离腓骨骨移植,用于延迟牙种植修复。

结论

报告并讨论了手术及技术细节,以及使用多孔钛植入物进行下颌骨重建的新趋势,并回顾了该主题的文献报告。已获得满意的功能和美容修复效果,且未发生重大并发症。该患者目前处于18个月的临床及放射学随访中,近期已通过种植体支持的全牙弓假牙完成功能恢复计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60e8/9871153/68bc473ab94d/40902_2023_374_Fig1_HTML.jpg

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