Hardouin P, Flipo R M, Foissac-Gegoux P, Thevenon A, Pouyol F, Duquesnoy B, Delcambre B
Service de Rhumatologie, Hôpital de la Charité, Lille, France.
J Rheumatol. 1987 Aug;14(4):780-3.
Eighty patients undergoing longterm hemodialysis were evaluated for joint function and radiographic abnormalities. Mean age of the population was 53 years, and mean duration of dialysis was 76 months (24 patients underwent dialysis for more than 10 years). Fifty-eight patients (72%) had joint symptoms; nonspecific arthralgia was the most frequent. Fifteen patients had morning stiffness and interrupted sleep due to arthralgias (shoulders 9, fingers 3) and 10 patients had diminished finger mobility. Radiographic evaluation showed 7 classes of lesions which are not characteristic of renal osteodystrophy or degenerative lesions, including erosive arthropathies of the fingers (8%), multiple carpal bone cysts (10%), cysts of the humeral head (9%), cysts of the hip (11%), erosive spondyloarthropathies (9%), cervical spondylolisthesis (5%) and multiple diaphyseal lacunae (1%). Overall, 42 distinct radiological lesions were observed in a total population of 23 patients. Twenty-nine of these lesions occurred in patients undergoing dialysis for at least 10 years. Certain clinical and radiological patterns were frequently combined after dialysis for more than 10 years: carpal tunnel syndrome, inflammatory joint pain, bone cysts and spondyloarthropathies.
对80例接受长期血液透析的患者进行了关节功能和影像学异常评估。研究人群的平均年龄为53岁,平均透析时间为76个月(24例患者透析时间超过10年)。58例患者(72%)有关节症状;非特异性关节痛最为常见。15例患者因关节痛出现晨僵并影响睡眠(肩部9例,手指3例),10例患者手指活动度降低。影像学评估显示7类病变,这些病变并非肾性骨营养不良或退行性病变的特征性表现,包括手指侵蚀性关节病(8%)、多发性腕骨囊肿(10%)、肱骨头囊肿(9%)、髋关节囊肿(11%)、侵蚀性脊柱关节病(9%)、颈椎滑脱(5%)和多发性骨干腔隙(1%)。总体而言,在23例患者中总共观察到42种不同的放射学病变。其中29种病变发生在透析至少10年的患者中。透析超过10年后,某些临床和放射学模式经常合并出现:腕管综合征、炎性关节疼痛、骨囊肿和脊柱关节病。