2019 - 2020年埃及开罗卡斯尔·阿莱尼多发性硬化症治疗中心营养咨询对多发性硬化症患者人体测量学指标及饮食摄入的影响：随机对照临床试验

Impact of nutrition counseling on anthropometry and dietary intake of multiple sclerosis patients at Kasr Alainy Multiple Sclerosis Unit, Cairo, Egypt 2019-2020: randomized controlled clinical trial.

作者信息

Afifi Zeinab, Hassan Amr, Abdelrahman Nebal, El Sayed Asmaa, Salem Marwa

机构信息

Department of Public Health and Community Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.

Department of Neurology, Faculty of Medicine, Cairo University, Cairo, Egypt.

出版信息

Arch Public Health. 2023 Jan 23;81(1):11. doi: 10.1186/s13690-022-01013-y.

DOI:10.1186/s13690-022-01013-y

PMID:36691061

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9869589/

Abstract

BACKGROUND

Faulty dietary habits and overnutrition are prevalent among Egyptian patients with multiple sclerosis (MS) who do not receive nutrition care as part of treatment. Thus, this study was conducted to identify the effect of nutrition counseling on the nutritional status of patients with MS. This endeavor might provide evidence for the value of counseling in such a setting and advance the integration of nutrition counseling into the routine management of patients with MS.

METHODS

A single-blinded, parallel-randomized controlled clinical trial was conducted at Kasr Alainy MS Unit on 120 eligible patients with MS from September 2019 to February 2020. Patients were randomly allocated to either the nutrition counseling intervention group (IG) or the control group (CG). Allocation concealment was performed by using sequentially numbered opaque sealed envelopes. All patients were assessed initially and complied with the Kasr Alainy MS Unit standard management protocol for the study period. Only patients in the IG underwent initial nutrition counseling sessions followed by a monthly evaluation. All patients were assessed at the end of the 3-month follow-up period. Sociodemographic data were gathered through a structured interview. Nutritional status was assessed anthropometrically and via 24-h recall. The 2 groups were compared initially and at the end of the follow-up. Both intention-to-treat and per-protocol analyses were conducted.

RESULTS

At baseline assessment, the prevalence of overweight and obesity was 31.7% and 32.5%, respectively, and the mean body mass index was 27.7 ± 5.7 kg/m. Mean waist circumference was 93.5 ± 11.9 and 99.2 ± 13.1 cm for males and females, respectively. Approximately 27.3% of males and 83.9% of females showed abdominal obesity. After 3 months of counseling, weight, body mass index, waist circumference, nutrient intake and adequacy significantly improved in the IG (p < 0.05).

CONCLUSION

Nutrition counseling significantly improved anthropometric measurements, dietary habits, nutrient intake and adequacy.

TRIAL REGISTRATION

The study was registered on ClinicalTrial.gov and was given a code (NCT04217564).

摘要

背景

在未接受营养护理作为治疗一部分的埃及多发性硬化症（MS）患者中，不良饮食习惯和营养过剩现象普遍存在。因此，本研究旨在确定营养咨询对MS患者营养状况的影响。这一努力可能为在这种情况下咨询的价值提供证据，并推动将营养咨询纳入MS患者的常规管理。

方法

2019年9月至2020年2月，在卡斯尔·阿莱尼MS科对120名符合条件的MS患者进行了一项单盲、平行随机对照临床试验。患者被随机分配到营养咨询干预组（IG）或对照组（CG）。采用顺序编号的不透明密封信封进行分配隐藏。所有患者在研究期间均接受了初始评估，并遵循卡斯尔·阿莱尼MS科的标准管理方案。只有IG组的患者接受了初始营养咨询，随后每月进行评估。在3个月随访期结束时对所有患者进行评估。通过结构化访谈收集社会人口学数据。通过人体测量和24小时回顾法评估营养状况。在随访开始时和结束时对两组进行比较。进行了意向性分析和符合方案分析。

结果

在基线评估时，超重和肥胖的患病率分别为31.7%和32.5%，平均体重指数为27.7±5.7kg/m²。男性和女性的平均腰围分别为93.5±11.9cm和99.2±13.1cm。约27.3%的男性和83.9%的女性存在腹型肥胖。咨询3个月后，IG组的体重、体重指数、腰围、营养素摄入量和充足率均有显著改善（p<0.05）。