饮食调整联合营养教育及咨询对多发性硬化代谢共病的影响:对临床实践和研究的启示。
Dietary Modification Combined with Nutrition Education and Counseling for Metabolic Comorbidities in Multiple Sclerosis: Implications for Clinical Practice and Research.
机构信息
School of Medical, Indigenous and Health Sciences, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.
Clinical Nutrition Department, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Saudi Arabia.
出版信息
Curr Nutr Rep. 2024 Jun;13(2):106-112. doi: 10.1007/s13668-024-00538-8. Epub 2024 Apr 27.
PURPOSE OF REVIEW
Metabolic comorbidities such as obesity, diabetes, hypertension, and dyslipidemia are common to multiple sclerosis (MS) and are associated with negative outcomes of the disease. Dietary intervention has the potential to improve MS co-morbidities; thus, it is a high priority for people living with MS to self-manage their disease. The present review aimed to summarize the recent evidence on the impacts of combining dietary modification with nutrition education and counseling on managing metabolic comorbidity markers in MS.
RECENT FINDINGS
Evidence suggests important roles for tailored dietary change strategies and nutrition education and counseling in managing metabolic comorbidities for MS. There is also indirect evidence suggesting a relationship between dietary fiber, the gut microbiome, and improved metabolic markers in MS, highlighting the need for more research in this area. For people living with MS, addressing both barriers and facilitators to dietary changes through behavior change techniques can help them achieve sustainable and tailored dietary behavior changes. This will support person-centered care, ultimately improving metabolic comorbidity outcomes. Metabolic comorbidities in MS are considered modifiable diseases that can be prevented and managed by changes in dietary behavior. However, the impact of targeted dietary interventions on mitigating MS-related metabolic comorbidities remains inadequately explored. Therefore, this review has provided insights into recommendations to inform future best practices in MS. Further well-designed studies based on tailored dietary strategies applying behavior change theories are needed to address the underlying determinants of dietary practice in this population.
目的综述
肥胖症、糖尿病、高血压和血脂异常等代谢性合并症在多发性硬化症(MS)中较为常见,并且与疾病的不良结局相关。饮食干预有可能改善 MS 合并症;因此,管理这些合并症是 MS 患者自我管理疾病的重中之重。本综述旨在总结关于将饮食改变与营养教育和咨询相结合,管理 MS 代谢性合并症标志物的最新证据。
最近的发现
证据表明,针对特定人群的饮食改变策略、营养教育和咨询在管理 MS 的代谢性合并症方面具有重要作用。也有间接证据表明膳食纤维、肠道微生物群与 MS 中代谢标志物的改善有关,这突显了该领域需要开展更多研究。对于 MS 患者,通过行为改变技术来解决饮食改变的障碍和促进因素,可以帮助他们实现可持续和个性化的饮食行为改变。这将支持以人为本的护理,最终改善代谢性合并症的结局。MS 中的代谢性合并症被认为是可以通过饮食行为改变来预防和管理的可改变疾病。然而,针对饮食干预对减轻 MS 相关代谢性合并症的影响仍研究不足。因此,本综述提供了有关建议的见解,以告知 MS 的未来最佳实践。需要进一步设计基于针对特定人群的饮食策略的、应用行为改变理论的研究,以解决该人群中饮食实践的潜在决定因素。