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伸展、支撑和设备治疗非手术关节骨关节炎相关关节挛缩的系统评价和荟萃分析。

Stretching, Bracing, and Devices for the Treatment of Osteoarthritis-Associated Joint Contractures in Nonoperated Joints: A Systematic Review and Meta-Analysis.

机构信息

Department of Physical Medicine and Rehabilitation, Elisabeth Bruyère Hospital, Ottawa, Ontario, Canada.

Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

出版信息

Sports Health. 2023 Nov-Dec;15(6):867-877. doi: 10.1177/19417381221147281. Epub 2023 Jan 23.

Abstract

CONTEXT

Many patients with osteoarthritis (OA) develop range of motion (ROM) restrictions in their affected joints (contractures), associated with worse outcomes and rising healthcare costs. Effective treatment guidance for lost ROM in OA-affected joints is lacking.

OBJECTIVE

A systematic review and meta-analysis evaluating the effectiveness of stretching and/or bracing protocols on native (nonoperated) joint ROM in the setting of radiographically diagnosed OA.

DATA SOURCES

Seven databases, English-language.

STUDY SELECTION

Studies including participants with radiographically diagnosed OA in any native joint evaluating the effect of stretching or bracing on ROM.

STUDY DESIGN

Systematic review and meta-analysis.

LEVEL OF EVIDENCE

Level 2.

DATA EXTRACTION

Two reviewers independently screened articles for inclusion and assessed risk of bias in included trials. Primary outcomes were ROM, pain, and adverse events (AEs).

RESULTS

We identified 6284 articles. A total of 9 randomized controlled trials, all evaluating the knee, met eligibility criteria. For stretching, 3 pooled studies reported total ROM, which improved by mean difference (MD) of 9.3° (95% CI 5.0°,13.5°) versus controls. Two pooled studies showed improved knee flexion ROM (MD 10.8° [7.3°,14.2°]) versus controls. Five studies were pooled for knee extension with mean improvement 9.1° [3.4°,14.8°] versus controls. Seven pooled studies showed reduced pain (standardized MD 1.9 [1.2,2.6]). One study reported improved knee extension of 3.7° [2.9°,4.5°] with use of a device. No studies used orthoses. One study reported on AEs, with none noted. Performance bias was present in all included studies, and only 3 studies clearly reported blinding of outcome assessors. Strength of evidence for primary outcomes was considered moderate.

CONCLUSION

There was moderate-quality evidence that stretching is an effective strategy for improving knee total, flexion and extension ROM, and pain. Our findings suggest that stretching to regain joint ROM in OA is not futile and that stretching appears to be an appropriate conservative intervention to improve patient outcomes as part of a comprehensive knee OA treatment plan before arthroplasty.

摘要

背景

许多骨关节炎(OA)患者的受累关节(挛缩)活动范围(ROM)受限,与较差的结局和不断上升的医疗保健成本相关。对于 OA 受累关节的 ROM 丧失,缺乏有效的治疗指导。

目的

系统评价和荟萃分析评估在影像学诊断的 OA 背景下,伸展和/或支具方案对原发性(未手术)关节 ROM 的有效性。

数据来源

7 个数据库,英语。

研究选择

包括任何原发性关节中有影像学诊断为 OA 的患者的研究,评估伸展或支具对 ROM 的影响。

研究设计

系统评价和荟萃分析。

证据水平

2 级。

数据提取

两名审查员独立筛选文章纳入标准,并评估纳入试验的偏倚风险。主要结局是 ROM、疼痛和不良事件(AE)。

结果

我们共确定了 6284 篇文章。共有 9 项随机对照试验全部评估膝关节,符合入选标准。对于伸展,3 项汇总研究报告了总 ROM,与对照组相比,平均差值(MD)改善了 9.3°(95%CI 5.0°,13.5°)。2 项汇总研究显示膝关节屈曲 ROM 改善(MD 10.8°[7.3°,14.2°])与对照组相比。5 项研究汇总显示膝关节伸展的平均改善为 9.1°(3.4°,14.8°)与对照组相比。7 项汇总研究显示疼痛减轻(标准化 MD 1.9 [1.2,2.6])。一项研究报告使用设备可使膝关节伸展改善 3.7°(2.9°,4.5°)。没有研究使用矫形器。一项研究报告了 AE,没有发现。所有纳入的研究都存在执行偏倚,只有 3 项研究明确报告了结果评估者的盲法。主要结局的证据强度被认为是中等。

结论

有中等质量的证据表明伸展是一种有效的策略,可以改善膝关节的总屈伸 ROM 和疼痛。我们的研究结果表明,在 OA 中恢复关节 ROM 的伸展并非徒劳,并且在关节置换术前,作为全面膝关节 OA 治疗计划的一部分,伸展似乎是一种改善患者结局的适当保守干预措施。

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