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Neurons as stromal drivers of nervous system cancer formation and progression.神经元作为神经系统癌症发生和进展的基质驱动因素。
Dev Cell. 2023 Jan 23;58(2):81-93. doi: 10.1016/j.devcel.2022.12.011.
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Update on connexins and gap junctions in neurons and glia in the mammalian nervous system.哺乳动物神经系统中神经元和神经胶质细胞中连接蛋白和缝隙连接的最新进展。
Brain Res Brain Res Rev. 2004 Dec;47(1-3):191-215. doi: 10.1016/j.brainresrev.2004.05.005.
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Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host.缝隙连接通讯为移植的神经干细胞与宿主之间的早期功能和有益相互作用提供了基础。
Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5184-9. doi: 10.1073/pnas.0915134107. Epub 2010 Feb 10.
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Design principles of electrical synaptic plasticity.电突触可塑性的设计原则。
Neurosci Lett. 2019 Mar 16;695:4-11. doi: 10.1016/j.neulet.2017.09.003. Epub 2017 Sep 8.
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Connexin-36 gap junctions mediate electrical coupling between ventral tegmental area GABA neurons.连接蛋白36间隙连接介导腹侧被盖区GABA能神经元之间的电偶联。
Synapse. 2006 Jul;60(1):20-31. doi: 10.1002/syn.20272.
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Pathways of neuron-astrocyte interactions and their possible role in neuroprotection.神经元-星形胶质细胞相互作用的途径及其在神经保护中的可能作用。
Eur Arch Psychiatry Clin Neurosci. 2001 Aug;251(4):159-69. doi: 10.1007/s004060170036.
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Gap Junctions in the Brain: Hardwired but Functionally Versatile.脑内缝隙连接：硬连线但功能多样
Neuroscientist. 2023 Oct;29(5):554-568. doi: 10.1177/10738584221120804. Epub 2022 Sep 20.
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Structural and Intermolecular Associations Between Connexin36 and Protein Components of the Adherens Junction-Neuronal Gap Junction Complex.连接蛋白 36 与黏着连接-神经元缝隙连接复合体质子成分之间的结构和分子间的联系。
Neuroscience. 2018 Aug 1;384:241-261. doi: 10.1016/j.neuroscience.2018.05.026. Epub 2018 Jun 5.
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Electrical synapses in mammalian CNS: Past eras, present focus and future directions.哺乳动物中枢神经系统中的电突触：过去的时代、当前的焦点和未来的方向。
Biochim Biophys Acta Biomembr. 2018 Jan;1860(1):102-123. doi: 10.1016/j.bbamem.2017.05.019. Epub 2017 Jun 1.
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Innexins in the lobster stomatogastric nervous system: cloning, phylogenetic analysis, developmental changes and expression within adult identified dye and electrically coupled neurons.龙虾口胃神经系统中的间隙连接蛋白：克隆、系统发育分析、发育变化以及在成体已鉴定的染料耦合和电耦合神经元中的表达
Eur J Neurosci. 2006 Dec;24(11):3119-33. doi: 10.1111/j.1460-9568.2006.05209.x.
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Circulating levels of glutamate predict brain disease in patients with advanced lung and breast cancer: a prospective study.晚期肺癌和乳腺癌患者循环中谷氨酸水平可预测脑部疾病：一项前瞻性研究。
J Neurooncol. 2025 Nov;175(2):825-836. doi: 10.1007/s11060-025-05182-y. Epub 2025 Jul 28.
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Neurotransmitter power plays: the synaptic communication nexus shaping brain cancer.神经递质的力量发挥：塑造脑癌的突触通讯枢纽
Acta Neuropathol Commun. 2025 Apr 30;13(1):85. doi: 10.1186/s40478-025-02009-9.
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The Spatial Distribution of Brain Metastasis Is Determined by the Heterogeneity of the Brain Microenvironment.脑转移瘤的空间分布由脑微环境的异质性决定。
Hum Brain Mapp. 2024 Dec 15;45(18):e70103. doi: 10.1002/hbm.70103.
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Navigating glioblastoma complexity: the interplay of neurotransmitters and chromatin.探索胶质母细胞瘤的复杂性：神经递质与染色质的相互作用。
Mol Biol Rep. 2024 Aug 17;51(1):912. doi: 10.1007/s11033-024-09853-3.
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Differential gene expression underlying epileptogenicity in patients with gliomas.胶质瘤患者致痫性背后的基因差异表达
Neurooncol Adv. 2024 Jun 21;6(1):vdae103. doi: 10.1093/noajnl/vdae103. eCollection 2024 Jan-Dec.
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A designer peptide against the EAG2-Kvβ2 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma.一种针对 EAG2-Kvβ2 钾通道的设计肽靶向癌细胞和神经元的相互作用，以治疗神经胶质瘤。
Nat Cancer. 2023 Oct;4(10):1418-1436. doi: 10.1038/s43018-023-00626-8. Epub 2023 Sep 11.
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Hsa_circRNA_0084043 promoting tumorigenesis in glioma through miR-577 sponging.Hsa_circRNA_0084043通过吸附miR-577促进神经胶质瘤的肿瘤发生。
Heliyon. 2023 Aug 17;9(9):e19219. doi: 10.1016/j.heliyon.2023.e19219. eCollection 2023 Sep.
本文引用的文献
1
Autonomous rhythmic activity in glioma networks drives brain tumour growth.胶质瘤网络中的自主节律活动驱动脑肿瘤生长。
Nature. 2023 Jan;613(7942):179-186. doi: 10.1038/s41586-022-05520-4. Epub 2022 Dec 14.
2
Cancer cells co-opt nociceptive nerves to thrive in nutrient-poor environments and upon nutrient-starvation therapies.癌细胞利用伤害性神经在营养匮乏的环境中以及在营养饥饿疗法下存活。
Cell Metab. 2022 Dec 6;34(12):1999-2017.e10. doi: 10.1016/j.cmet.2022.10.012. Epub 2022 Nov 16.
3
Cancer Neuroscience: Evidence for a New Hallmark of Cancer.癌症神经科学：癌症新特征的证据
Adv Biol (Weinh). 2022 Sep;6(9):e2200192. doi: 10.1002/adbi.202200192.
4
Glioblastoma hijacks neuronal mechanisms for brain invasion.胶质母细胞瘤利用神经元机制进行脑侵袭。
Cell. 2022 Aug 4;185(16):2899-2917.e31. doi: 10.1016/j.cell.2022.06.054. Epub 2022 Jul 31.
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Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1.神经元过度兴奋驱动神经纤维瘤病 1 型模型中中枢和外周神经系统肿瘤的进展。
Nat Commun. 2022 May 19;13(1):2785. doi: 10.1038/s41467-022-30466-6.
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Reversible CD8 T cell-neuron cross-talk causes aging-dependent neuronal regenerative decline.可逆性CD8 T细胞与神经元的相互作用导致衰老依赖性神经元再生能力下降。
Science. 2022 May 13;376(6594):eabd5926. doi: 10.1126/science.abd5926.
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Olfactory sensory experience regulates gliomagenesis via neuronal IGF1.嗅觉感知体验通过神经元 IGF1 调节神经胶质瘤发生。
Nature. 2022 Jun;606(7914):550-556. doi: 10.1038/s41586-022-04719-9. Epub 2022 May 11.
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Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice.p53基因缺陷导致成年小鼠初级体感皮层神经元的结构、功能及突触缺陷。
Front Mol Neurosci. 2022 Apr 7;15:871974. doi: 10.3389/fnmol.2022.871974. eCollection 2022.
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Decoupling astrocytes in adult mice impairs synaptic plasticity and spatial learning.成年小鼠的星形胶质细胞解偶联会损害突触可塑性和空间学习能力。
Cell Rep. 2022 Mar 8;38(10):110484. doi: 10.1016/j.celrep.2022.110484.
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Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development.星型胶质细胞-神经元通过 Hedgehog 信号转导相互作用调节皮质突触发育。
Cell Rep. 2022 Feb 22;38(8):110416. doi: 10.1016/j.celrep.2022.110416.
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