Eryıldız Canan, Tarladaçalısır Taner, Kuyucuklu Gulcan, Çakmakçı Berrak, Sakru Nermin
Department of Medical Microbiology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Department of Medical Services and Techniques, Health Services Vocational School, Trakya University, Edirne, Turkey.
Iran J Parasitol. 2022 Oct-Dec;17(4):517-524. doi: 10.18502/ijpa.v17i4.11279.
Parasites of the genus are common worldwide and are important cestodes that cause serious infections in humans and animals. This retrospective study evaluated the indirect hemagglutination (IHA) test results of serum samples obtained from patients with a pre-diagnosis of cystic echinococcosis (CE) within ten years. In addition, the role of the IHA test results of the patients in the follow-up of the treatment and determining possible recurrences was investigated.
The IHA test results of 2426 serum samples of patients with a pre-diagnosed CE admitted to Trakya University Health Center for Medical Research and Practice in Edirne, Turkey, between January 2011 and December 2020 were evaluated retrospectively. The data of 53 patients with CE who had medical treatment and/or postoperative follow-up serological records were evaluated.
Of 2426 IHA tests, 376 (15.5%) were seropositive, and 2050 (84.5%) were seronegative. It was determined that 376 serum samples detected as positive belonged to 207 patients with CE. Of 207 CE patients, 109 (52.7%) were female and 98 (47.3%) were male. The most common organ involvement was the liver in 186 (89.9%) cases. Of 53 patients, 16 were considered relapse cases. The median follow-up period for 16 recurrent cases was 31.8 (1-77) months. Our results showed a statistically significant correlation between long-term serological follow-up and recurrence detection (=0.034).
Long-term serological follow-up after treatment is considered useful in determining possible recurrent cases. CE is an important public health problem for endemic regions, including our country, and we think our study results will contribute to the status and follow-up of the disease.
属寄生虫在全球范围内普遍存在，是引起人类和动物严重感染的重要绦虫。本回顾性研究评估了10年内囊性棘球蚴病（CE）预诊断患者血清样本的间接血凝试验（IHA）结果。此外，还研究了患者IHA检测结果在治疗随访和确定可能复发中的作用。
回顾性评估2011年1月至2020年12月期间入住土耳其埃迪尔内特拉凯亚大学健康中心进行医学研究和实践的2426例预诊断为CE患者的血清样本的IHA检测结果。对53例接受药物治疗和/或术后随访血清学记录的CE患者的数据进行了评估。
在2426次IHA检测中，376例（15.5%）血清学呈阳性，2050例（84.5%）血清学呈阴性。确定检测为阳性的376份血清样本属于207例CE患者。在207例CE患者中，109例（52.7%）为女性，98例（47.3%）为男性。最常见的器官受累是肝脏，共186例（89.9%）。53例患者中，16例被认为是复发病例。16例复发病例的中位随访期为31.8（1 - 77）个月。我们的结果显示长期血清学随访与复发检测之间存在统计学显著相关性（=0.034）。
治疗后的长期血清学随访被认为有助于确定可能的复发病例。CE是包括我国在内的流行地区的一个重要公共卫生问题，我们认为我们的研究结果将有助于了解该疾病的现状和随访。
