Department of Internal Medicine, Nowon Eulji Medical Center, Eulji University College of Medicine, Seoul, Korea.
Clin Mol Hepatol. 2023 Feb;29(Suppl):S150-S156. doi: 10.3350/cmh.2022.0362. Epub 2023 Jan 25.
Nonalcoholic fatty liver disease (NAFLD) affects approximately 30% of the population worldwide and includes nonalcoholic fatty liver, nonalcoholic steatohepatitis (NASH), and cirrhosis. Since NAFLD-associated diseases begin with steatosis, the early diagnosis of steatosis helps to prevent the progression of NASH and fibrosis. In addition, more convenient and easily diagnosable serum biomarkers are becoming crucial in disease diagnosis. In this report, we summarize the known serum biomarkers for liver steatosis and provide guidance for their application in clinical practice.
非酒精性脂肪性肝病(NAFLD)影响着全球约 30%的人口,包括非酒精性脂肪肝、非酒精性脂肪性肝炎(NASH)和肝硬化。由于与 NAFLD 相关的疾病始于脂肪变性,因此早期诊断脂肪变性有助于阻止 NASH 和纤维化的进展。此外,更方便和易于诊断的血清生物标志物在疾病诊断中变得至关重要。在本报告中,我们总结了已知的用于诊断肝脂肪变性的血清生物标志物,并为它们在临床实践中的应用提供了指导。