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PLOS Glob Public Health. 2022 Jan 4;2(1):e0000149. doi: 10.1371/journal.pgph.0000149. eCollection 2022.
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坦桑尼亚北部的宫颈癌——感染艾滋病毒的女性了解些什么。

Cervical cancer in Northern Tanzania-What do women living with HIV know.

作者信息

Mrema Dorah, Ngocho James Samwel, Mremi Alex, Amour Maryam, Machange Rogathe, Shayo Benjamin C, Alloyce Julius P, Ndosi Evaline, Shirima Beatus T, Fande Device, Shehoza Rahma, Balandya Emmanuel, Sunguya Bruno, Mshana Stephen E, Mteta Alfred K, Lyamuya Eligius, Bartlett John, Mmbaga Blandina T

机构信息

Kilimanjaro Christian Medical University College, Moshi, Kilimanjaro, Tanzania.

Department of Obstetrics and Gynaecology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

出版信息

Front Oncol. 2023 Jan 9;12:957325. doi: 10.3389/fonc.2022.957325. eCollection 2022.

DOI:10.3389/fonc.2022.957325
PMID:36698389
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9868899/
Abstract

BACKGROUND

Cervical cancer (CC) is more prevalent in women living with human immunodeficiency virus (HIV) infection compared to the general population. The magnitude is high among all countries burdened with HIV-Tanzania is no exception. Despite the unprecedented risk, women living with HIV (WLHIV) may not be aware of the risk and might have unfounded beliefs thereof. This study aimed to determine the knowledge, awareness, and beliefs on CC screening among WLHIV attending a clinic at the Kilimanjaro Christian Medical Centre (KCMC) in Northern Tanzania.

METHODS

This hospital-based cross-sectional study was conducted among 327 WLHIV attending care and treatment clinic (CTC) at KCMC. A pre-tested questionnaire was used to collect quantitative data. Both descriptive and regression methods were used to determine CC knowledge, awareness, and beliefs as well as factors associated with knowledge of CC among WLHIV using SPSS version 23.

RESULTS

Participants' mean age was 46 ± 10.4 years. Although just half (54.7%) of WLHIV had insufficient knowledge of CC, the majority of the participants (83.5%) were able to recognize at least three risk factors, but with limited understanding of symptoms and prevention. The majority held positive beliefs on CC and screening practices. Factors associated with good knowledge of CC included being married (AOR: 3.66, 95% CI: 1.84-7.28), having used ART for at least 2 years (AOR: 4.08, 95% CI: 1.36-12.21), and having previously screened for CC (AOR: 1.62, 95% CI: 1.01-2.59).

CONCLUSION

WLHIV attending care and treatment center had insufficient knowledge about CC screening. To further improve screening and treatment for CC, at both facility and community levels, targeted awareness and education campaigns are warranted.

摘要

背景

与普通人群相比,宫颈癌(CC)在感染人类免疫缺陷病毒(HIV)的女性中更为普遍。在所有负担着HIV的国家中,这一比例都很高——坦桑尼亚也不例外。尽管存在前所未有的风险,但感染HIV的女性(WLHIV)可能并未意识到这种风险,并且可能对此存在毫无根据的看法。本研究旨在确定在坦桑尼亚北部乞力马扎罗基督教医疗中心(KCMC)就诊的感染HIV女性对CC筛查的知识、意识和看法。

方法

这项基于医院的横断面研究在327名在KCMC接受护理和治疗诊所(CTC)治疗的感染HIV女性中进行。使用预先测试的问卷收集定量数据。使用描述性和回归方法,通过SPSS 23版本确定感染HIV女性对CC的知识、意识和看法以及与CC知识相关的因素。

结果

参与者的平均年龄为46±10.4岁。虽然只有一半(54.7%)的感染HIV女性对CC知识不足,但大多数参与者(83.5%)能够识别至少三种风险因素,但对症状和预防的理解有限。大多数人对CC和筛查做法持有积极看法。与对CC有良好了解相关的因素包括已婚(调整后比值比:3.66,95%置信区间:1.84-7.28)、使用抗逆转录病毒疗法至少2年(调整后比值比:4.08,95%置信区间:1.36-12.21)以及之前接受过CC筛查(调整后比值比:1.62,95%置信区间:1.01-2.59)。

结论

在护理和治疗中心就诊的感染HIV女性对CC筛查知识不足。为了在机构和社区层面进一步改善CC的筛查和治疗,有必要开展有针对性的宣传和教育活动。