Evsen Ali, Karahan Mehmet Zülkif
Cardiology, Dağkapı State Hospital, Diyarbakır, TUR.
Cardiology, Mardin Artuklu University Faculty of Medicine, Mardin, TUR.
Cureus. 2022 Dec 23;14(12):e32890. doi: 10.7759/cureus.32890. eCollection 2022 Dec.
The frontal QRS-T angle (fQRS-T) is linked to myocardial ischemia and ventricular arrhythmias. On the other hand, non-dipper hypertension is a risk factor for cardiac adverse events. The objective of this research was to determine whether the fQRS-T, a marker of ventricular heterogeneity, could be used to predict non-dipper hypertensive individuals in the lack of left ventricular hypertrophy.
The observational study was carried out retrospectively. Patients diagnosed with hypertension were included in this study. Blood tests were routinely conducted for all patients. Electrocardiography (ECG) was conducted for each patient and echocardiography was performed. Blood pressure (BP) values were collected from the ambulatory Holter records. According to ambulatory Holter monitoring, the individuals were separated into two groups. The association between fQRS-T and hypertension was investigated.
The research involved 123 patients, with an average age of 51.85±8.22 years, comprising 76 women (61.8%) and 47 males (38.2%). According to ambulatory Holter monitoring, patients were separated into dippers (n=65) and non-dippers (n=58). There were no statistically significant in the laboratory and echocardiographic variables (p>0.05). QT dispersion (QTd) and fQRS-T were substantially greater in the non-dipper group than in the dipper group (p=0.043 and p<0.001, respectively). Independent determinants of non-dipper status were determined by univariate and multivariate logistic regression analyses. fQRS-T was found to be the only independent indicator of non-dipper status (OR: 1.03, 95%CI: 1.02-1.06, p<0.001).
The fQRS-T may be a useful marker for estimating non-dipper hypertensive individuals in the lack of left ventricular hypertrophy.
额面QRS-T角（fQRS-T）与心肌缺血及室性心律失常相关。另一方面，非勺型高血压是心脏不良事件的一个危险因素。本研究的目的是确定作为心室异质性标志物的fQRS-T是否可用于预测无左心室肥厚的非勺型高血压个体。
本观察性研究为回顾性研究。纳入诊断为高血压的患者。对所有患者进行常规血液检查。对每位患者进行心电图（ECG）检查并进行超声心动图检查。从动态心电图记录中收集血压（BP）值。根据动态心电图监测，将个体分为两组。研究fQRS-T与高血压之间的关联。
本研究纳入123例患者，平均年龄51.85±8.22岁，其中女性76例（61.8%），男性47例（38.2%）。根据动态心电图监测，患者分为勺型（n=65）和非勺型（n=58）。实验室和超声心动图变量无统计学显著差异（p>0.05）。非勺型组的QT离散度（QTd）和fQRS-T显著高于勺型组（分别为p=0.043和p<0.001）。通过单因素和多因素逻辑回归分析确定非勺型状态的独立决定因素。发现fQRS-T是唯一的非勺型状态独立指标（OR：1.03，95%CI：1.02-1.06，p<0.001）。
fQRS-T可能是评估无左心室肥厚的非勺型高血压个体的有用标志物。
