Postgraduate Program in Medicines and Pharmaceutical Assistance, Faculty of Pharmacy, Federal University of Minas Gerais-Belo Horizonte/MG, Belo Horizonte, Brazil.
Department of Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais-Belo Horizonte/MG, Belo Horizonte, Brazil.
Environ Sci Pollut Res Int. 2023 Mar;30(11):28506-28524. doi: 10.1007/s11356-023-25455-1. Epub 2023 Jan 26.
Over time, a growing increase in human pollutants in the aquatic environment has been observed. The global presence of residues in water bodies reinforces the need to develop improved methods to detect them and evaluate their ecotoxicological effects in aquatic environments. Thus, this study aimed to present the main assays using Biomphalaria glabrata as a biological model for ecotoxicological studies. We performed a systematic literature review with data published up to June 2022 on the Web of Science, SCOPUS, Science Direct, PubMed, and SciELO databases. Thirty studies were selected for this review after screening. Biomphalaria glabrata has been studied as an ecotoxicological model for different substances through toxicity, embryotoxicity, cytotoxicity, genotoxicity, and bioaccumulation assays. Studies evaluating the impact of B. glabrata exposure to several substances have reported effects on their offspring, as well as toxicity and behavioral and reproductive effects. This review presents various assays using B. glabrata as a biological model for ecotoxicological studies. The use of a representative species of ecosystems from tropical regions is a necessary tool for tropical environmental monitoring. It was observed that the freshwater snail B. glabrata was effective for the evaluation of the ecotoxicity of several types of chemical substances, but further studies are needed to standardize the model.
随着时间的推移，在水生环境中观察到人类污染物的数量不断增加。水体中残留物的全球性存在，加强了开发改进方法来检测它们并评估它们在水生环境中的生态毒理学效应的必要性。因此，本研究旨在介绍使用光滑滨螺（Biomphalaria glabrata）作为生态毒理学研究的生物模型的主要检测方法。我们对截至 2022 年 6 月在 Web of Science、SCOPUS、Science Direct、PubMed 和 SciELO 数据库上发表的数据进行了系统的文献综述。经过筛选，共有 30 项研究被纳入本综述。通过毒性、胚胎毒性、细胞毒性、遗传毒性和生物累积性检测，光滑滨螺已被研究作为不同物质的生态毒理学模型。评估光滑滨螺暴露于多种物质对其后代的影响、毒性以及行为和生殖影响的研究报告了许多研究结果。本综述介绍了使用光滑滨螺作为生态毒理学研究生物模型的各种检测方法。使用来自热带地区生态系统的代表性物种是热带环境监测的必要工具。研究表明，淡水蜗牛光滑滨螺对于评估几种类型的化学物质的生态毒性是有效的，但需要进一步的研究来标准化该模型。
