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关于准父亲产前基因检测医保覆盖的伦理论证

An Ethical Argument for Health Insurance Coverage of Paternal Prenatal Genetic Testing.

作者信息

Nguyen Michelle T, Campo-Engelstein Lisa, Lee Richard H, Nguyen Brian T

机构信息

Division of Maternal-Fetal Medicine and the Division of Family Planning, Department of Obstetrics and Gynecology, Keck School of Medicine of the University of Southern California, Los Angeles, California; and the Department of Bioethics & Health Humanities, School of Public and Population Health, University of Texas Medical Branch, Galveston, Texas.

出版信息

Obstet Gynecol. 2023 Jan 1;141(1):11-14. doi: 10.1097/AOG.0000000000005018. Epub 2022 Nov 30.

Abstract

Despite evidence-based recommendations from the American College of Obstetricians and Gynecologists and the American College of Medical Genetics to offer prenatal genetic carrier screening for reproductive partners, partner carrier screening or genetic testing is inconsistently covered by pregnant patients' health insurance plans. Health policies that exclude reproductive partners from insurance coverage for prenatal carrier screening or genetic testing contradict multiple ethical principles and can even contribute to adverse maternal-child health outcomes. Incomplete or missing information regarding partner carrier status can lead to costly, invasive, and potentially risky interventions for the pregnant patient that can be avoided by a simple and less expensive blood test in the reproductive partner. Lack of information regarding carrier status also harms the neonate by obviating an opportunity for early detection and treatment of potential medical complications. Insurance policies that exclude coverage for paternal genetic testing perpetuate the disproportionate burdens of pregnancy care and risk shouldered by pregnant people. To rectify these ethical dilemmas, partner carrier screening and genetic testing should be considered and covered as routine components of obstetric health care that are covered by health insurance.

摘要

尽管美国妇产科医师学会和美国医学遗传学学会给出了基于证据的建议,即为生育伴侣提供产前基因携带者筛查,但孕妇的健康保险计划对伴侣携带者筛查或基因检测的覆盖情况并不一致。将生育伴侣排除在产前携带者筛查或基因检测保险范围之外的健康政策违背了多项伦理原则,甚至可能导致母婴不良健康结局。关于伴侣携带者状态的信息不完整或缺失,可能会导致对孕妇进行代价高昂、侵入性强且有潜在风险的干预措施,而通过对生育伴侣进行简单且成本较低的血液检测就可以避免这些干预。由于缺乏携带者状态的信息,新生儿早期发现和治疗潜在医疗并发症的机会也被剥夺,这同样对新生儿造成了伤害。将父亲基因检测排除在保险范围之外的保险政策,使孕妇承担了不成比例的妊娠护理负担和风险。为纠正这些伦理困境,应将伴侣携带者筛查和基因检测视为产科医疗保健的常规组成部分,并纳入健康保险覆盖范围。

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