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本文引用的文献

1
Comparative study of articaine and lidocaine without palatal injection for maxillary teeth extraction.上颌牙拔除时不腭侧注射阿替卡因与利多卡因的对比研究。
Clin Oral Investig. 2019 Aug;23(8):3239-3248. doi: 10.1007/s00784-018-2738-x. Epub 2018 Nov 12.
2
Anesthetic efficacy of 4% articaine and 2% lignocaine in achieving palatal anesthesia following a single buccal infiltration during periodontal therapy: A randomized double-blind split-mouth study.4%阿替卡因和2%利多卡因在牙周治疗单次颊侧浸润后实现腭部麻醉的麻醉效果:一项随机双盲半口研究。
J Anaesthesiol Clin Pharmacol. 2018 Jan-Mar;34(1):107-110. doi: 10.4103/joacp.JOACP_200_15.
3
The Anesthetic Efficacy of Articaine and Lidocaine in Equivalent Doses as Buccal and Non-Palatal Infiltration for Maxillary Molar Extraction: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial.阿替卡因和利多卡因等效剂量用于上颌磨牙拔除颊侧及非腭侧浸润麻醉的效果:一项随机、双盲、安慰剂对照临床试验
J Oral Maxillofac Surg. 2018 Apr;76(4):737-743. doi: 10.1016/j.joms.2017.11.028. Epub 2017 Nov 27.
4
Comparative evaluation of the efficacy of lignocaine containing topical anesthetic agents during extraction of deciduous anterior teeth.含利多卡因的局部麻醉剂在乳牙前牙拔除术中疗效的比较评估。
Minerva Stomatol. 2018 Feb;67(1):26-31. doi: 10.23736/S0026-4970.17.04052-3. Epub 2017 Oct 9.
5
Recent advances in topical anesthesia.局部麻醉的最新进展。
J Dent Anesth Pain Med. 2016 Dec;16(4):237-244. doi: 10.17245/jdapm.2016.16.4.237. Epub 2016 Dec 31.
6
Effect of Topical Anesthesia with Lidocaine-prilocaine (EMLA) Cream and Local Pressure on Pain during Infiltration Injection for Maxillary Canines: A Randomized Double-blind clinical trial.利多卡因-丙胺卡因(EMLA)乳膏局部麻醉及局部压迫对上颌尖牙浸润注射时疼痛的影响:一项随机双盲临床试验。
J Contemp Dent Pract. 2016 Jul 1;17(7):592-6.
7
Recent advances and perspectives in topical oral anesthesia.局部口腔麻醉的最新进展与展望
Expert Opin Drug Deliv. 2017 May;14(5):673-684. doi: 10.1080/17425247.2016.1227784. Epub 2016 Sep 1.
8
Extraction of Maxillary Teeth Using Articaine Without a Palatal Injection: A Comparison Between the Anterior and Posterior Regions of the Maxilla.使用阿替卡因不进行腭部注射拔除上颌牙:上颌前部与后部的比较
J Oral Maxillofac Surg. 2017 Jan;75(1):87-91. doi: 10.1016/j.joms.2016.06.192. Epub 2016 Jul 21.
9
Updates of Topical and Local Anesthesia Agents.局部麻醉剂的更新
Dent Clin North Am. 2016 Apr;60(2):445-71. doi: 10.1016/j.cden.2015.12.001.
10
Topical anesthesia.局部麻醉。
J Anaesthesiol Clin Pharmacol. 2015 Oct-Dec;31(4):450-6. doi: 10.4103/0970-9185.169049.

EMLA作为上颌牙拔除术中替代腭部注射的局部麻醉剂的临床疗效:一项随机对照试验。

The Clinical Efficacy of EMLA as a Topical Anesthetic Agent Instead of Palatal Injection During Maxillary Dental Extractions: A Randomized Controlled Trial.

作者信息

Chugh Ankita, Singh Surjit, Khatana Shruti, Gaur Shubham, Patnana Arun Kumar, Chugh Vinay, Kumar Pravin

机构信息

Department of Dentistry, AIIMS, Jodhpur, India.

Department of Pharmacology, AIIMS, Jodhpur, India.

出版信息

J Maxillofac Oral Surg. 2023 Mar;22(1):172-177. doi: 10.1007/s12663-021-01633-x. Epub 2021 Aug 22.

DOI:10.1007/s12663-021-01633-x
PMID:36703663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9871143/
Abstract

BACKGROUND

Even after the invention of the modern injection techniques, palatal injection still remains a painful experience for patients, and this pain is attributed to the presence of rich nerve complement and displacement of tightly adherent palatal mucosa during anesthesia.

AIM

To check the clinical efficacy of EMLA as a topical anesthetic agent instead of palatal injection during maxillary dental extractions.

METHODOLOGY

The trial includes a total of 102 participants, in whom maxillary molar extractions were indicated, were randomly divided into the experimental group (eutectic mixture of local anesthesia (EMLA) topical application was used along with buccal injection) and control group (palatal injection along with buccal injection). Pain perception during extraction was recorded using the visual analog scale (VAS).

RESULTS

Mean VAS score for 'injection' in control group patients was 5.2 ± 2.08 in contrast to no pain in experimental group. In experimental group, mean VAS score on 'probing' was 0.92 ± 1.50. VAS score on 'extraction' in EMLA group was little higher though the difference was not statistically significant. The overall experience using Liekert's scale was higher in experimental group (4.0 ± 0.76) as compared to (3.3 ± 0.82) in control group leading to higher overall satisfaction among patients who underwent extraction in the experimental group.

CONCLUSION

EMLA application produced a satisfactory level of anesthesia in the palatal tissue when compared with the palatal injection.

摘要

背景

即使现代注射技术已经发明,但对上颌患者来说,腭部注射仍是一种痛苦的体验,这种疼痛归因于腭部丰富的神经分布以及麻醉过程中紧密附着的腭黏膜移位。

目的

检查在拔除上颌牙时,复方利多卡因乳膏(EMLA)作为局部麻醉剂替代腭部注射的临床疗效。

方法

该试验共纳入102名有上颌磨牙拔除指征的参与者,随机分为试验组(采用复方利多卡因乳膏局部应用联合颊部注射)和对照组(腭部注射联合颊部注射)。拔牙过程中的疼痛感受采用视觉模拟评分法(VAS)记录。

结果

对照组患者“注射”时的平均VAS评分为5.2±2.08,而试验组无疼痛。试验组“探查”时的平均VAS评分为0.92±1.50。复方利多卡因乳膏组“拔牙”时的VAS评分略高,尽管差异无统计学意义。试验组使用李克特量表的总体体验(4.0±0.76)高于对照组(3.3±0.82),导致试验组拔牙患者的总体满意度更高。

结论

与腭部注射相比,应用复方利多卡因乳膏能使腭部组织达到满意的麻醉水平。