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4%阿替卡因和2%利多卡因在牙周治疗单次颊侧浸润后实现腭部麻醉的麻醉效果:一项随机双盲半口研究。

Anesthetic efficacy of 4% articaine and 2% lignocaine in achieving palatal anesthesia following a single buccal infiltration during periodontal therapy: A randomized double-blind split-mouth study.

作者信息

Ashwath Balachandran, Subramoniam Sundaram, Vijayalakshmi Rajaram, Shanmugam Muthukali, Priya Bagavathiperumal Meena, Anitha Vijayarangan

机构信息

Department of Periodontics, Chettinad Dental College and Research Institute, Kelambakkam, Kancheepuram, India.

Periodontist, Private Dental Practice, Chennai, Tamil Nadu, India.

出版信息

J Anaesthesiol Clin Pharmacol. 2018 Jan-Mar;34(1):107-110. doi: 10.4103/joacp.JOACP_200_15.

DOI:10.4103/joacp.JOACP_200_15
PMID:29643633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5885423/
Abstract

BACKGROUND

The aim of this randomized split-mouth double-blind study was to evaluate whether 4% articaine hydrochloride with 1:100,000 epinephrine administered as a single buccal infiltration in the maxillary posterior sextant can provide palatal anesthesia when compared with 2% lignocaine with 1:100,000 epinephrine during scaling and root planing and access flap surgery (AFS).

MATERIAL AND METHODS

A total of 40 patients with chronic generalized periodontitis requiring periodontal therapy in the maxillary posterior sextants were recruited in this study. About 4% articaine and 2% lignocaine were administered as buccal infiltration in a split-mouth design randomly. The pain scores in the palatal aspect were recorded during scaling and root planing and open flap debridement using Heft-Parker visual analog scale. The onset of anesthesia was also recorded and compared.

RESULTS

The success rate for maxillary buccal infiltration to induce palatal anesthesia using articaine was 90% during scaling and root planing and 82.5% during AFS and for lignocaine solution was 20% and 15%, respectively. The difference between the two agents was statistically significant ( < 0.05). The onset of anesthesia between articaine and lignocaine was also found to be statistically significant ( < 0.05).

CONCLUSION

In this study, we observed that the efficacy of 4% articaine was superior to 2% lignocaine to induce palatal anesthesia following maxillary buccal infiltration in maxillary posterior sextants.

摘要

背景

本随机双盲半口对照研究旨在评估,在上颌后牙区进行龈上洁治、根面平整及翻瓣手术(AFS)时,与1:100,000肾上腺素配比的2%利多卡因相比,1:100,000肾上腺素配比的4%盐酸阿替卡因单次颊侧浸润注射能否提供腭部麻醉。

材料与方法

本研究共纳入40例需要对上颌后牙区进行牙周治疗的慢性广泛性牙周炎患者。采用半口对照设计,随机对一侧颊侧进行4%阿替卡因和2%利多卡因浸润注射。使用赫夫特 - 帕克视觉模拟量表记录龈上洁治、根面平整及开放瓣清创过程中腭部的疼痛评分。同时记录并比较麻醉起效时间。

结果

在龈上洁治和根面平整过程中,阿替卡因诱导腭部麻醉的上颌颊侧浸润成功率为90%,在AFS过程中为82.5%;利多卡因溶液的成功率分别为20%和15%。两种药物之间的差异具有统计学意义(<0.05)。阿替卡因和利多卡因的麻醉起效时间差异也具有统计学意义(<0.05)。

结论

在本研究中,我们观察到,在上颌后牙区进行上颌颊侧浸润后,4%阿替卡因诱导腭部麻醉的效果优于2%利多卡因。

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本文引用的文献

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Efficacy of 4% articaine hydrochloride and 2% lignocaine hydrochloride in the extraction of maxillary premolars for orthodontic reasons.4%盐酸阿替卡因与2%盐酸利多卡因用于正畸原因拔除上颌前磨牙的疗效
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The efficacy and safety of articaine versus lignocaine in dental treatments: a meta-analysis.阿替卡因与利多卡因在牙科治疗中的疗效和安全性:荟萃分析。
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Comparison of anesthetic efficacy of 4% articaine and 2% lidocaine for maxillary buccal infiltration in patients with irreversible pulpitis.4%阿替卡因与2%利多卡因对上颌不可逆性牙髓炎患者进行颊侧浸润麻醉的效果比较。
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The anesthetic efficacy of articaine in buccal infiltration of mandibular posterior teeth.阿替卡因在下颌后牙颊侧浸润麻醉中的麻醉效果。
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Onset and duration periods of articaine and lidocaine on maxillary infiltration.阿替卡因和利多卡因对上颌浸润麻醉的起效时间和持续时间。
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