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基质性角膜炎在一家三级眼科医院单纯疱疹性角膜炎患者中的表现:一项描述性横断面研究。

Stromal Keratitis among Herpes Simplex Keratitis Patients in a Tertiary Eye Hospital: A Descriptive Cross-sectional Study.

机构信息

Department of Cornea and External Eye Disease, Nepal Eye Hospital, Tripureshwor, Kathmandu, Nepal.

Nepal Eye Hospital, Tripureshwor, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2022 Dec 1;60(256):1008-1010. doi: 10.31729/jnma.7906.

Abstract

INTRODUCTION

The manifestations of herpes simplex virus keratitis range from epithelial keratitis to vision-threatening stromal keratitis. There are limited studies done on our part regarding stromal keratitis. The aim of the study was to find out the prevalence of stromal keratitis among herpes simples keratitis patients in a tertiary eye hospital.

METHODS

This descriptive cross-sectional study was conducted among patients who presented with herpes simplex virus keratitis in a tertiary eye hospital between 1 January 2020 to 28 February 2022. Ethical clearance was taken from Ethical Review Board (Reference number: 1/2079/80). Data was collected from hospital records which was reviewed and visual acuity at presentation and at one-month follow-up, clinical details on examination were recorded and, diagnosis of the stage of disease given in the case record was noted. Convenience sampling was used. Point estimate and 95% Confidence Interval were calculated.

RESULTS

Among 112 Herpes simplex keratitis patients, the prevalence of stromal keratitis was 38 (33.93%) (25.16-42.70, 95% Confidence Interval).

CONCLUSIONS

The prevalence of stromal keratitis among patients of herpes simplex keratitis was similar to studies conducted in similar settings.

KEYWORDS

herpes simplex keratitis; keratitis; prevalence.

摘要

简介

单纯疱疹病毒性角膜炎的表现范围从上皮性角膜炎到威胁视力的基质性角膜炎。我们在基质性角膜炎方面的研究有限。本研究旨在探讨在一家三级眼科医院中单纯疱疹性角膜炎患者中基质性角膜炎的患病率。

方法

这是一项在 2020 年 1 月 1 日至 2022 年 2 月 28 日期间在一家三级眼科医院就诊的单纯疱疹病毒角膜炎患者中进行的描述性横断面研究。本研究已获得伦理审查委员会的批准(编号:1/2079/80)。数据来自医院记录,对记录进行了审查,并记录了就诊时和一个月随访时的视力、检查时的临床详细信息,并注意到病例记录中给出的疾病阶段诊断。采用便利抽样。计算了点估计值和 95%置信区间。

结果

在 112 例单纯疱疹性角膜炎患者中,基质性角膜炎的患病率为 38 例(33.93%)(25.16-42.70,95%置信区间)。

结论

单纯疱疹性角膜炎患者中基质性角膜炎的患病率与类似环境下的研究相似。

关键词

单纯疱疹性角膜炎;角膜炎;患病率。

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本文引用的文献

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Classification of herpes simplex virus keratitis.单纯疱疹病毒性角膜炎的分类。
Cornea. 1999 Mar;18(2):144-54. doi: 10.1097/00003226-199903000-00002.

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