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免费药物的获取是否降低了医疗体系成本?对希望药房计划的评估。

Does access to free medication reduce health system costs? An evaluation of the Dispensary of Hope program.

机构信息

RTI International, Research Triangle Park, NC.

Dispensary of Hope, Nashville, TN.

出版信息

J Manag Care Spec Pharm. 2023 Feb;29(2):187-196. doi: 10.18553/jmcp.2023.29.2.187.

Abstract

Cost-related medication nonadherence-when patients fail to take medication as prescribed because of the cost of the medication-has numerous consequences: more hospitalizations, avoidable deaths, and greater health care expenditures. Dispensary of Hope is a charitable medication access program that collects and distributes pharmaceuticals to pharmacies to dispense free of charge to patients with no insurance, low incomes, and chronic conditions. To estimate the differences in medical costs and utilization of hospital patients enrolled in the Dispensary of Hope program relative to those who were not enrolled. We used administrative claims data from 2 health systems participating in Dispensary of Hope to identify those in the program and a comparison group, respectively. Claims data included emergency department (ED) encounters, inpatient encounters, costs, and prescriptions. Health system 1 (HS1) data began July 1, 2016, and ended December 31, 2019; health system 2 (HS2) data ran from March 10, 2014, to December 31, 2019. Program enrollment dates (index dates) were identified via program registration or prescription fills. We propensity score weighted a comparison population from HS1 and HS2, respectively, to match program patient demographic and comorbidity characteristics. We estimated changes in costs, ED visits, inpatient stays, and primary care sensitive ED visits over time between the 2 groups (difference-indifference) over 18 months preenrollment and postenrollment. HS1 comparison (n = 6,714) and Dispensary of Hope (n = 880) groups were balanced on age, sex, race and ethnicity, and comorbidities; both populations were approximately 46 years old, 43% female, 64% White, with an average of 3.0 comorbidities. The HS2 samples were almost 50 years old and a majority female (56%) and Black (55%). Per-person annual costs at HS1 decreased by $3,161 ( < 0.05) more in the Dispensary of Hope group than in the comparison group from the preenrollment to the postenrollment period. Inpatient stays decreased by 200 stays per 1,000 patients per year ( = 0.02) and ED visits increased by 0.32 ( < 0.01) on a yearly basis relative to the comparison group. Primary care sensitive ED visits increased over the period. No results were statistically significant in HS2. We found substantial reductions in costs and inpatient stays for Dispensary of Hope HS1 participants, and we did not find significant results at HS2. Differences between the health systems or patient populations could explain these varying results. Our study represents a rigorous, multistate evaluation that highlights the impact of a charitable medication access program on hospital utilization for the medically underserved population. The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: this work was funded and supported by Dispensary of Hope.

摘要

由于药物费用,患者未按照规定服用药物而导致的用药相关不依从性(即药物依从性差)会产生诸多后果:更多的住院治疗、可避免的死亡和更高的医疗保健支出。“希望药房”是一个慈善药物获取项目,该项目收集和分发药品,免费提供给没有保险、收入低和患有慢性病的患者。

为了评估参加“希望药房”项目的住院患者与未参加该项目的患者的医疗费用和利用情况的差异。我们使用了参与“希望药房”项目的两个医疗系统的行政索赔数据来分别确定参加项目和对照组的患者。索赔数据包括急诊(ED)就诊、住院就诊、费用和处方。医疗系统 1(HS1)的数据从 2016 年 7 月 1 日开始,到 2019 年 12 月 31 日结束;医疗系统 2(HS2)的数据从 2014 年 3 月 10 日运行到 2019 年 12 月 31 日。项目登记日期(索引日期)是通过项目登记或处方填写确定的。我们分别从 HS1 和 HS2 中对比较人群进行倾向评分加权,以匹配项目患者的人口统计学和合并症特征。我们估计了两组(差异-差异)在 18 个月的预登记和登记后在成本、ED 就诊、住院和初级保健敏感 ED 就诊方面的变化。

HS1 对照组(n=6714)和“希望药房”组(n=880)在年龄、性别、种族和民族以及合并症方面平衡;两组人群均约 46 岁,43%为女性,64%为白人,平均合并症为 3.0 种。HS2 样本的年龄几乎为 50 岁,大多数为女性(56%)和黑人(55%)。与对照组相比,HS1 组的个人年费用在登记前到登记后的期间内减少了 3161 美元(<0.05)。每年住院人数减少 200 人/千名患者(=0.02),ED 就诊次数每年增加 0.32 次(<0.01)。与对照组相比,初级保健敏感 ED 就诊次数有所增加。HS2 中没有统计学意义的结果。

我们发现“希望药房”HS1 参与者的成本和住院费用大幅降低,而 HS2 中没有显著结果。医疗系统或患者群体之间的差异可能解释了这些不同的结果。我们的研究代表了一项严格的、多州评估,强调了慈善药物获取项目对医疗服务不足人群的医院利用的影响。

作者披露了这项研究的以下财务支持

这项工作得到了“希望药房”的资助和支持。

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